Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle

BIS-CAPRYLOYLOXYPALMITAMIDO ISOPROPANOL.

Essential CAS 1883454-19-0 / SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING

A high-performance synthetic pseudoceramide engineered to replicate the precise molecular architecture of the skin's natural lipid mantle. It acts as a structural architect, reinforcing the stratum corneum to prevent moisture loss and shield against environmental stressors.

skin-identical lipid emollient barrier repair agent skin protectant

Science

This lipid utilizes Multi-Lamellar Emulsion (MLE) technology to mimic the 'cross-shaped' lamellar patterns found in healthy human skin. By integrating directly into the lipid bilayer, it fills microscopic gaps in the skin barrier, effectively decreasing transepidermal water loss (TEWL) and restoring structural integrity.


Research

High confidence
Effective range 0.3–8%
Optimal

2%

Key findings

  1. 01 Clinical trials of a 2% triple ceramide complex demonstrated rapid fortification of the skin barrier and significant relief for hyper-sensitive skin types.
  2. 02 High-concentration lipid complexes (approx. 8%) achieved an 84% barrier repair rate within just 2 hours and nearly 100% recovery after 14 days of use.

Transparency

Commonly dusted
Min. effective
0.3%
Red flag below
0.1%

While beneficial for texture at low levels, therapeutic barrier repair requires concentrations of at least 0.3% to 2%. Formulas listing this far below the 1% line often lack the structural density needed for clinical-grade repair.


The Formula

Solubility
Oil
Optimal pH 4 – 7
0 7 14

Stability

Exhibits superior thermal stability, maintaining emulsion integrity through extreme temperature fluctuations ranging from -25°C to +50°C.

Synergies

  • Cholesterol
  • Fatty Acids
  • Natural Ceramides

Conflicts

  • High concentrations of electrolytes
  • Strong salts

Safety

CIR Status
Not reviewed
Pregnancy
Safe
Sensitization risk Low

Extensively utilized in hypoallergenic infant care and post-procedure medical ointments; recognized as safe by South Korean MFDS for compromised skin.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Essential

A gold-standard barrier repair lipid that offers the structural precision required for clinical-grade skin fortification.


Related

Finding similar ingredients…