Science
Mechanism of Action
This extract operates through a multifaceted biological pathway: it inhibits the 5α-reductase enzyme to mitigate hormone-driven hair thinning and activates key growth factors like VEGF and KGF for follicle repair. For the skin, it suppresses lipid synthesis in sebocytes to reduce oiliness, neutralizes oxidative stress via quercitrin and myricitrin content, and triggers the MAPK/TGF-β pathways to accelerate fibroblast proliferation.
Research
Clinical Evidence
High confidence0.005%
Key findings
- 01 In vitro analysis showed that concentrations as low as 0.0025% to 0.005% significantly inhibited sebum generation and reduced lipid droplet size in sebocytes.
- 02 A 0.01% water extract demonstrated the ability to boost human dermal fibroblast proliferation to 138% compared to control groups, indicating strong wound-healing potential.
- 03 A 16-week randomized controlled trial confirmed a significant increase in hair count (p=0.006) when utilizing the extract within an exosome-based delivery system.
Transparency
Dusting Analysis
Because biological activity is documented at exceptionally low thresholds (0.0025%), many brands include it at 'trace' levels to claim benefits. At Moumoujus, we consider levels below 0.0025% as 'dusting' that may fail to trigger the required sebocyte or fibroblast response.
The Formula
Formulation
Stability
The extract is naturally rich in minerals which can increase electrical conductivity; this may destabilize ionic emulsions or reduce the viscosity of certain surfactant systems. It is also prone to oxidative darkening if not properly stabilized.
Synergies
- Zinc PCA
- Niacinamide
- Hyaluronic Acid
- Peptides
Conflicts
- High ionic strength systems
- Cationic surfactants
- Strong oxidizing agents
Safety
Safety Profile
While generally safe and non-irritating, it contains natural shikimic acid. In high-concentration scalp applications, this may cause mild tingling or itching in hypersensitive individuals.
Your Skin
Skin Compatibility
Our Assessment
Verdict
An expertly balanced botanical that offers scientifically-backed sebum control and cellular regeneration even at very low inclusion rates.
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References
Sources