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BIOSACCHARIDE GUM-5.

Valuable CAS - / SKIN CONDITIONING

A high-performance microbial polysaccharide derived via sugar fermentation that creates a breathable, protective film on the skin's surface. This biotechnology-driven ingredient provides a 'second skin' effect to lock in moisture while imparting a refined, silky sensory profile.

Skin-conditioning Humectant Film-forming Viscosity controlling

Science

As a high molecular weight humectant and film-former, it captures environmental moisture into the stratum corneum while physically obstructing trans-epidermal water loss (TEWL). Beyond hydration, its fermented glucose and rhamnose structure interacts with keratinocytes to potentially soothe the skin and support a healthy microbiome environment.


Research

High confidence
Effective range 0.5–5%
Optimal

3%

Key findings

  1. 01 Clinical HRIPT testing across a 0.5-5% range confirmed the ingredient is non-sensitizing and non-irritating, even for reactive skin types.
  2. 02 Studies at 1-3% concentrations demonstrate significant reduction in TEWL through non-occlusive film formation, providing both immediate and sustained hydration.

Transparency

Not commonly dusted
Min. effective
1%
Red flag below
0.5%

While effective as a texture enhancer at lower levels, therapeutic hydration and barrier protection require concentrations of at least 1%. Formulations using it below 0.5% are likely leveraging it for marketing claims rather than clinical skin benefits.


The Formula

Solubility
Water
Optimal pH 5 – 7
0 7 14

Stability

Exhibits excellent thermal stability and resilience against pH fluctuations; non-ionic nature ensures compatibility with electrolytes.

Synergies

  • Glycerin
  • Hyaluronic Acid
  • Non-ionic surfactants

Conflicts

  • High ethanol concentrations
  • High loads of strong cationic surfactants

Safety

CIR Status
Safe as used
Max tested
3%
Pregnancy
Safe
Sensitization risk Low

Its large molecular size prevents systemic absorption, making it an exceptionally safe topical agent with negligible penetration risk.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A sophisticated, non-irritating film-former that provides essential moisture retention and a superior skin feel without the occlusion of traditional waxes.


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References