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Moumoujus

BIFIDOBACTERIUM/LACTOBACILLUS/STREPTOCOCCUS/PANAX NOTOGINSENG RHIZOME/ROOT EXTRACT FERMENT FILTRATE.

Valuable / ANTIOXIDANT, HUMECTANT, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SURFACTANT - EMULSIFYING

A high-precision biotechnological ferment that fuses Traditional Chinese Medicine with modern probiotic science. By utilizing a triple-strain bacterial system to biotransform Panax Notoginseng, this filtrate delivers concentrated, bioavailable metabolites that reinforce the skin barrier and modulate inflammatory pathways.

Summary

Antioxidant Soothing agent Humectant Skin-conditioning agent Barrier repair

Science

Mechanism of Action

The fermentation process utilizes Bifidobacterium, Lactobacillus, and Streptococcus to enzymatically break down complex ginsenosides into smaller, highly active molecules like Compound K and Ginsenoside Rd. These metabolites downregulate NF-κB signaling to suppress pro-inflammatory cytokines while probiotic-derived postbiotics stimulate the synthesis of Type I collagen and hyaluronic acid, simultaneously balancing the cutaneous microbiome.

Research

Clinical Evidence

High confidence
Effective range 2–5%
Optimal

3%

Key findings

  1. 01 Application at 2.0%-5.0% demonstrated significant suppression of TNF-α, IL-1β, and IL-6 cytokines alongside increased expression of essential barrier proteins filaggrin and involucrin.
  2. 02 In vivo testing at 3.0% concentration resulted in a 24% boost in hydration levels and a 15% reduction in trans-epidermal water loss (TEWL) over a 28-day period.
  3. 03 Clinical observation noted visible improvements in skin luminosity and overall tone uniformity following consistent use.

Transparency

Dusting Analysis

Commonly dusted
Min. effective
2%
Red flag below
0.5%

Due to the prestige and cost associated with triple-strain fermented Panax Notoginseng, many formulations include it at 'label claim' levels (below 0.5%). However, clinical data suggests a minimum threshold of 2.0% is required to trigger significant barrier protein synthesis and anti-inflammatory benefits.

The Formula

Formulation

Solubility
Water
Optimal pH 4 – 6.5
0 7 14

Stability

The extract is thermo-sensitive; exposure to temperatures exceeding 50°C may degrade bioactive metabolites. It should be incorporated during the cooling phase of production (below 40°C).

Synergies

  • Hyaluronic Acid
  • Niacinamide
  • Ceramides
  • Peptides

Conflicts

  • Strong oxidizing agents
  • High-proof alcohol (above 20%)
  • Extreme pH environments (<3.5 or >8.0)

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
5%
Pregnancy
Safe
Sensitization risk Low

While the complex itself is pending formal CIR review, the individual components—Panax Notoginseng and bacterial ferments—have extensive safety records. It is NMPA approved and listed in the EU CosIng database.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

An exceptionally potent bio-active ingredient for systemic barrier repair and inflammation control when formulated at or above 2%.

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