Science
Mechanism of Action
It functions as a dual-action biological humectant. Primarily, it upregulates the HAS2 gene to trigger endogenous hyaluronic acid synthesis within dermal fibroblasts, while simultaneously catalyzing the production of cornified envelope proteins to seal the skin barrier. Furthermore, it modulates the skin microbiome by producing short-chain fatty acids that support natural repair processes.
Research
Clinical Evidence
High confidence3%
Key findings
- 01 Demonstrated significant reduction in transepidermal water loss (TEWL) and measurable hydration increases over 28 days at a 3% concentration.
- 02 In-vitro evidence of stimulated hyaluronic acid synthesis and increased cornified envelope protein production for enhanced barrier resilience.
Transparency
Dusting Analysis
Due to its premium nature and efficacy at low percentages, many formulas include it below 1% for 'label claims' without achieving the threshold required to trigger the HAS2 gene expression seen in clinical trials.
The Formula
Formulation
Stability
Highly robust and heat-stable; unlike live probiotics, it maintains bioactivity under standard shelf conditions. Should be incorporated below 40°C to ensure structural integrity of the polysaccharide chains.
Synergies
- Hyaluronic Acid
- Niacinamide
- Ceramides
- Peptides
Conflicts
- Ethanol (high concentrations)
- Strong cationic surfactants
- Extreme acidity (pH < 3.0)
Safety
Safety Profile
Classified as GRAS (Generally Regarded as Safe). As a non-living bacterial fraction, it poses no risk of infection or over-colonization common with live cultures.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A superior, stable postbiotic that transitions skin from passive hydration to active, endogenous moisture production.
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References
Sources