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BIFIDA/DEER ANTLER FERMENT FILTRATE.

Valuable CAS - / SKIN CONDITIONING

A high-performance bioactive complex that fuses probiotic science with regenerative peptide technology. This specialized ferment filtrate provides a dual-action approach to skin health by reinforcing the microbiome while accelerating deep cellular repair.

Skin conditioning Soothing Barrier repair DNA repair stimulation Collagen synthesis

Science

This ingredient operates through a synergistic pathway: Bifida-derived peptidoglycans and acetic acid fortify the physical skin barrier and stimulate DNA repair enzymes to counter UV-induced damage. Simultaneously, deer antler peptides and growth factors (IGF-1) trigger collagen synthesis and modulate the TGF-β signaling pathway to promote scarless wound healing and enhance dermal elasticity.


Research

High confidence
Effective range 1–10%
Optimal

5%

Key findings

  1. 01 In vivo trials demonstrated a 20.62% reduction in TEWL and a 17.25% improvement in hydration over 28 days at a 1.0% concentration.
  2. 02 In vitro scratch assays showed a 96.73% cell migration rate, indicating exceptional potential for barrier restoration and wound closure.
  3. 03 Clinical application on reactive skin at 10.0% resulted in a significant decrease in sensitivity and marked improvement in overall barrier function.

Transparency

Commonly dusted
Min. effective
1%
Red flag below
0.5%

Due to the high cost of the deer antler fraction, brands often include this at sub-clinical levels (<0.5%) for marketing claims. Efficacy for barrier repair and redness reduction is scientifically validated starting at 1.0%.


The Formula

Solubility
Water
Optimal pH 4 – 6
0 7 14

Stability

Aqueous-stable but thermosensitive; exposure to temperatures exceeding 50°C may denature the regenerative peptides. Protect from direct UV light to maintain bioactive integrity.

Synergies

  • Hyaluronic acid
  • Ceramides
  • Niacinamide
  • Non-proteolytic peptides

Conflicts

  • Strong oxidizing agents
  • Highly acidic formulas (pH <3.0)
  • Proteolytic enzymes (Papain, Bromelain)

Safety

CIR Status
Safe as used
Pregnancy
Safe
Sensitization risk Low

While the specific combination is a newer INCI, its constituent ferments are recognized as safe by CIR (2023-2025). Low irritancy profile makes it suitable for post-procedure care.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A potent, multi-modal ingredient that excels at repairing the skin barrier and reducing inflammation through both probiotic and peptide-driven pathways.


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