Science
Mechanism of Action
This ingredient operates through a synergistic pathway: Bifida-derived peptidoglycans and acetic acid fortify the physical skin barrier and stimulate DNA repair enzymes to counter UV-induced damage. Simultaneously, deer antler peptides and growth factors (IGF-1) trigger collagen synthesis and modulate the TGF-β signaling pathway to promote scarless wound healing and enhance dermal elasticity.
Research
Clinical Evidence
High confidence5%
Key findings
- 01 In vivo trials demonstrated a 20.62% reduction in TEWL and a 17.25% improvement in hydration over 28 days at a 1.0% concentration.
- 02 In vitro scratch assays showed a 96.73% cell migration rate, indicating exceptional potential for barrier restoration and wound closure.
- 03 Clinical application on reactive skin at 10.0% resulted in a significant decrease in sensitivity and marked improvement in overall barrier function.
Transparency
Dusting Analysis
Due to the high cost of the deer antler fraction, brands often include this at sub-clinical levels (<0.5%) for marketing claims. Efficacy for barrier repair and redness reduction is scientifically validated starting at 1.0%.
The Formula
Formulation
Stability
Aqueous-stable but thermosensitive; exposure to temperatures exceeding 50°C may denature the regenerative peptides. Protect from direct UV light to maintain bioactive integrity.
Synergies
- Hyaluronic acid
- Ceramides
- Niacinamide
- Non-proteolytic peptides
Conflicts
- Strong oxidizing agents
- Highly acidic formulas (pH <3.0)
- Proteolytic enzymes (Papain, Bromelain)
Safety
Safety Profile
While the specific combination is a newer INCI, its constituent ferments are recognized as safe by CIR (2023-2025). Low irritancy profile makes it suitable for post-procedure care.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A potent, multi-modal ingredient that excels at repairing the skin barrier and reducing inflammation through both probiotic and peptide-driven pathways.
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References
Sources