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BETA-IONOL.

Valuable CAS 22029-76-1 / PERFUMING

Beta-ionol is a lipophilic terpene alcohol that functions as both a sophisticated fragrance component and a bioactive agent for skin rejuvenation. Its unique molecular structure allows it to target deep dermal architecture, specifically focusing on the restoration of density in the papillary layer.

Anti-glycation Dermal densifier Fragrance Antioxidant

Science

This ingredient operates as a modulator of nuclear hormone receptors (NHR) and an inhibitor of the NF-κB and MAPK signaling pathways. By dampening pro-inflammatory mediators like nitric oxide and TNF-α, it mitigates the 'inflammaging' process while providing antioxidant protection against oxidative stress.


Research

Medium confidence
Effective range 0.01–5%
Optimal

0.5%

Key findings

  1. 01 Patented research indicates efficacy in treating protein glycation within the skin matrix to restore dermal density.
  2. 02 In vitro data demonstrates potential anti-proliferative effects through cell cycle modulation in specific cell lines.
  3. 03 Cosmetic fragrance assessments establish 0.2-1% as the standard range for olfactory and soothing applications.

Transparency

Commonly dusted
Min. effective
0.01%
Red flag below
0.05%

Because Beta-ionol can be listed for its scent at very low concentrations, many products include it at 'dusting' levels (below 0.05%) where it provides a floral aroma but fails to deliver its patented anti-glycation and dermal-densifying benefits.


The Formula

Solubility
Oil
Optimal pH 6.5 – 8.4
0 7 14

Stability

Highly lipophilic with a logP near 4.3; stable in neutral to slightly alkaline environments but prone to rapid hydrolysis in acidic conditions below pH 3.5.

Synergies

  • Lipophilic antioxidants
  • Glycation inhibitors
  • Solubilizing oils

Conflicts

  • Strong oxidizing agents
  • Strongly acidic formulations
  • Purely aqueous systems

Safety

CIR Status
Not reviewed
Max tested
8%
Pregnancy
Safe
Sensitization risk Low

Recognized as safe by IFRA/RIFM for topical use; it has a high sensitization induction threshold (1700 µg/cm2).


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A dual-action terpene that offers both aromatic appeal and precise anti-aging benefits for dermal density, provided it is formulated at therapeutic levels.


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