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BETA-ASPARTYL ARGININE.

Valuable CAS 213250-52-3 / HAIR CONDITIONING, ORAL CARE, SKIN CONDITIONING

A high-performance bio-dipeptide sourced from blue-green algae that serves as a vital cellular energy precursor. This unique nitrogen-carrying molecule stabilizes the skin's internal environment while offering superior resistance to enzymatic breakdown compared to standard peptides.

skin conditioning antioxidant energy precursor anti-inflammatory

Science

It functions as a bioavailable 'nitrogen vehicle' that fuels skin regeneration and cellular homeostasis. By inhibiting matrix metalloproteinases (MMPs) and reducing pro-inflammatory IL-8 secretion, it effectively mitigates 'inflammaging' while its unique beta-linkage ensures prolonged activity within the skin layers.


Research

High confidence
Effective range 0.3–5%
Optimal

1%

Key findings

  1. 01 In vitro testing confirmed that a 0.3% (10 mM) concentration enhances ROS scavenging by 10-15% when paired with specific alkanediols.
  2. 02 Concentrations between 1.0% and 5.0% have been demonstrated to act as skin energy precursors, significantly supporting wound healing and tissue regeneration.

Transparency

Commonly dusted
Min. effective
0.3%
Red flag below
0.1%

While it shows antioxidant boosting at 0.3%, its structural and regenerative benefits as an energy precursor typically require 1.0% or higher. Formulas using only trace amounts likely miss the cellular homeostasis benefits.


The Formula

Solubility
Water
Optimal pH 4 – 7.5
0 7 14

Stability

Highly stable in aqueous systems and both O/W and W/O emulsions; its beta-peptide structure prevents degradation by common skin proteases.

Synergies

  • 1,2-heptanediol
  • Alkanediols
  • Antioxidants

Conflicts

  • Proteolytic enzymes
  • Strong oxidizing agents

Safety

CIR Status
Not reviewed
Pregnancy
Safe
Sensitization risk Low

Composed of two naturally occurring amino acids (aspartic acid and arginine), making it an exceptionally biocompatible and safe ingredient.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An expertly engineered dipeptide that provides robust protection against inflammatory aging and serves as a critical energy source for skin repair.


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