Science
Mechanism of Action
It functions as a bioavailable 'nitrogen vehicle' that fuels skin regeneration and cellular homeostasis. By inhibiting matrix metalloproteinases (MMPs) and reducing pro-inflammatory IL-8 secretion, it effectively mitigates 'inflammaging' while its unique beta-linkage ensures prolonged activity within the skin layers.
Research
Clinical Evidence
High confidence1%
Key findings
- 01 In vitro testing confirmed that a 0.3% (10 mM) concentration enhances ROS scavenging by 10-15% when paired with specific alkanediols.
- 02 Concentrations between 1.0% and 5.0% have been demonstrated to act as skin energy precursors, significantly supporting wound healing and tissue regeneration.
Transparency
Dusting Analysis
While it shows antioxidant boosting at 0.3%, its structural and regenerative benefits as an energy precursor typically require 1.0% or higher. Formulas using only trace amounts likely miss the cellular homeostasis benefits.
The Formula
Formulation
Stability
Highly stable in aqueous systems and both O/W and W/O emulsions; its beta-peptide structure prevents degradation by common skin proteases.
Synergies
- 1,2-heptanediol
- Alkanediols
- Antioxidants
Conflicts
- Proteolytic enzymes
- Strong oxidizing agents
Safety
Safety Profile
Composed of two naturally occurring amino acids (aspartic acid and arginine), making it an exceptionally biocompatible and safe ingredient.
Your Skin
Skin Compatibility
Our Assessment
Verdict
An expertly engineered dipeptide that provides robust protection against inflammatory aging and serves as a critical energy source for skin repair.
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References
Sources