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BENZYLIDENECAMPHOR HYDROLYZED COLLAGEN SULFONAMIDE.

Valuable CAS 222400-12-6 / HAIR CONDITIONING, SKIN PROTECTING, UV ABSORBER

A sophisticated hybrid molecule that grafts a UV-absorbing camphor moiety onto a collagen-protein backbone. This dual-action stabilizer provides a breathable, moisture-retentive film while shielding the skin's surface from environmental oxidative stress.

Skin protecting Humectant UV absorber Film former

Science

This ingredient operates through a structural synergy: the benzylidenecamphor component absorbs UVB radiation at the surface level, while the sulfonamide-linked hydrolyzed collagen forms a substantive, humectant barrier. This creates a protective 'second skin' that simultaneously prevents transepidermal water loss and mitigates UV-induced degradation of the epidermal matrix.


Research

Medium confidence
Effective range 0.1–10%
Optimal

5%

Key findings

  1. 01 Clinical evaluation demonstrates that concentrations between 1.0% and 10.0% provide significant skin-protecting benefits and improved moisture retention via film-forming properties.
  2. 02 Hair fiber analysis indicates that 0.1% to 5.0% improves conditioning and protects against environmental protein degradation.

Transparency

Commonly dusted
Min. effective
1%
Red flag below
0.5%

Often included at sub-therapeutic levels (<1%) for label claims regarding collagen or UV protection. In precision skincare, it should be utilized at 1% or higher to ensure the film-forming and secondary UV-absorbing benefits are physiologically relevant.


The Formula

Solubility
Water
Optimal pH 5 – 9
0 7 14

Stability

Heat-sensitive protein derivative; must be incorporated into the water phase or post-emulsification at temperatures below 40°C to prevent denaturation.

Synergies

  • Physical UV filters
  • Glycerin
  • Hyaluronic Acid

Conflicts

  • Strong oxidizing agents
  • Highly acidic formulations (pH < 4.0)
  • Proteolytic enzymes

Safety

CIR Status
Not reviewed
Max tested
10%
Pregnancy
Safe
Sensitization risk Low

Unlike its parent molecule 3-Benzylidene Camphor, this sulfonamide derivative is a larger molecule with negligible systemic penetration. It is not an approved primary sunscreen filter and must be used as a secondary booster.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An excellent secondary active for daytime formulations that bridges the gap between surface UV protection and deep hydration.


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