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BENZYL ISOBUTYRATE.

Optional CAS 103-28-6 / PERFUMING

A refined aromatic ester used to harmonize complex fragrance profiles and add a sophisticated fruity-floral depth to formulations. Beyond its olfactory properties, it functions as a specialized solvent that supports the stability of oil-soluble active ingredients.

Perfuming agent Solvent Fragrance modifier Carrier agent

Science

As a lipophilic ester, it serves as a bridging agent between top and heart fragrance notes, smoothing the transitions of synthetic florals. In a skincare matrix, it acts as a carrier and solvent, facilitating the even distribution and delivery of lipid-soluble compounds while maintaining formula integrity.


Research

Medium confidence
Effective range 0.5–6%
Optimal

1%

Key findings

  1. 01 RIFM assessments (2012/2016) demonstrated that a 4.17% concentration is non-irritating and non-sensitizing for human topical exposure.
  2. 02 Fraterworks formulation data indicates a 0.5-6% range is required for effective olfactory modification and smoothing of harsh floral notes.
  3. 03 NOAEL levels established at 150-200 mg/kg/day confirm a high systemic safety margin for repeated exposure.

Transparency

Not commonly dusted
Min. effective
0.1%
Red flag below
0.05%

Because it primarily serves as a fragrance modifier and secondary solvent, it is not usually 'dusted' for marketing claims; however, concentrations below 0.1% may fail to provide the intended carrier benefits or olfactory stabilization.


The Formula

Solubility
Oil
Optimal pH 4 – 7
0 7 14

Stability

Highly stable in neutral media but susceptible to hydrolysis in extreme acidic or alkaline environments. Cold-processing is recommended as temperatures exceeding 40°C can lead to volatilization.

Synergies

  • Benzyl acetate
  • Lipid-soluble antioxidants
  • Synthetic floral accords

Conflicts

  • Strong oxidizing agents
  • Strong acids
  • Strong alkalis

Safety

CIR Status
Safe as used
Max tested
4%
Pregnancy
Safe
Sensitization risk Low

IFRA safety standards restrict use to 1.0% in facial moisturizers and 2.1% in body lotions to minimize any potential for sensitization in high-exposure users.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Optional

A functional aromatic component that excels at refining the sensory profile of a product while assisting in the delivery of oil-based actives.


Related

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References