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Moumoujus

BENZOXIQUINE.

Avoid CAS 86-75-9 / ANTIMICROBIAL

Benzoxiquine is a specialized antimicrobial and antifungal agent primarily utilized in medicinal topical treatments for its ability to neutralize microbial threats. In skincare, it serves as a potent biocide, though its use is increasingly restricted due to evolving safety assessments and the availability of more stable alternatives.

Summary

antimicrobial biocide antifungal

Science

Mechanism of Action

It functions through a chelation process, where it binds to essential metal ions like magnesium, calcium, and zinc within microbial cells. This action starves bacteria and fungi of the minerals required for enzymatic function, effectively halting their growth and reproduction.

Research

Clinical Evidence

Low confidence
Effective range 0.06–2.5%
Optimal

2.5%

Key findings

  1. 01 Evaluated by the FDA for the treatment of fungal infections including tinea pedis and tinea cruris, though currently categorized as needing further data for definitive efficacy verification.

Transparency

Dusting Analysis

Not commonly dusted
Min. effective
0.06%
Red flag below
0.05%

Benzoxiquine is rarely found in standard cosmetic formulations; its presence at sub-clinical levels (below 0.06%) would likely serve only as a preservative rather than an active treatment for skin conditions.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Practically insoluble in water; requires alcohol-based or non-polar oil systems for successful delivery and stability.

Synergies

  • Alcohol-based delivery systems
  • Anhydrous gels

Conflicts

  • Metal ions
  • Strong oxidizing agents

Safety

Safety Profile

CIR Status
Insufficient data
Max tested
2.5%
Sensitization risk Moderate

Classified by ECHA as an irritant to skin and eyes. Concerns regarding potential mutagenicity in laboratory tests (Ames test) without metabolic activation have been noted.

Your Skin

Skin Compatibility

Yes Normal
No Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

While an effective antimicrobial in medical settings, its potential for irritation and insufficient safety data make it unsuitable for precision skincare.

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