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BENINCASA CERIFERA FRUIT EXTRACT.

Valuable CAS 97659-61-5 / SKIN CONDITIONING

Commonly known as Winter Melon, this botanical powerhouse serves as a multi-functional bioactive agent that accelerates cellular turnover while fortifying the skin's moisture barrier. It is a precise blend of protective polysaccharides and anti-inflammatory triterpenoids designed for high-performance recovery.

Antioxidant Skin conditioning Soothing Humectant

Science

The extract operates via a dual-action pathway: it activates the NRF2/HO-1 signaling system to neutralize oxidative stress while simultaneously inhibiting matrix-degrading enzymes like collagenase and hyaluronidase. This preserves the structural integrity of the dermis, while its high polysaccharide content acts as a biological humectant to increase epidermal hydration.


Research

High confidence
Effective range 0.1–5%
Optimal

4.2%

Key findings

  1. 01 A 4.2% concentration in a topical cream demonstrated significant stratum corneum renewal and visible anti-aging effects over an 11-day period.
  2. 02 In vitro studies confirmed that fruit-derived polysaccharides at 0.98 mg/mL effectively prevent H2O2-induced cell death in human dermal fibroblasts.

Transparency

Commonly dusted
Min. effective
1%
Red flag below
0.2%

Often listed at the bottom of ingredient decks for label appeal, this extract requires a concentration of at least 1-4% to deliver documented skin-renewal and antioxidant benefits.


The Formula

Solubility
Both
Optimal pH 4 – 6.5
0 7 14

Stability

Displays robust heat stability up to 45°C. Contains both water-soluble and oil-soluble components, making it exceptionally stable in oil-in-water (O/W) emulsions.

Synergies

  • Hyaluronic Acid
  • Vitamin C
  • Peptides

Conflicts

  • Strong oxidizing agents
  • Extreme pH environments

Safety

CIR Status
Not reviewed
Pregnancy
Safe
Sensitization risk Low

Classified as a safe skin conditioning agent in the EU; HET-CAM testing confirms it is non-irritating to both skin and mucous membranes.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A high-performance botanical that bridges the gap between traditional soothing extracts and precision anti-aging actives through enzymatic inhibition.


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