Science
Mechanism of Action
It functions by stimulating angiogenesis, the biological process of forming new micro-capillaries. By improving dermal microcirculation, it ensures a superior delivery of oxygen and vital nutrients to fibroblasts, which in turn accelerates cellular proliferation, wound healing, and the synthesis of essential structural proteins like collagen and elastin.
Research
Clinical Evidence
High confidence3%
Key findings
- 01 Clinical trials utilizing a 3% concentration demonstrated a 38% reduction in the depth of wrinkles and a 32% increase in elasticity within a 14-day window.
- 02 Immediate hydration metrics showed an 83% increase following topical application.
- 03 Research indicates a significant upregulation of barrier-essential proteins, specifically Filaggrin and Involucrin, when utilized in synergistic peptide blends.
Transparency
Dusting Analysis
Due to the high cost of recombinant growth factors, many brands include them at 'label-claim' levels (often below 0.1%) that lack the concentration required to trigger the biological signaling observed in clinical trials (1-3%).
The Formula
Formulation
Stability
Thermally sensitive molecule; it must be incorporated during the cool-down phase of production at temperatures not exceeding 40°C to maintain biological activity.
Synergies
- Other Recombinant Growth Factors (EGF, IGF-1)
- Polypeptide blends
- Hyaluronic Acid
- Amino Acids
Conflicts
- Proteolytic enzymes
- Strong oxidizing agents
- Extreme pH environments (<3.5 or >8.0)
- High heat (>40°C)
Safety
Safety Profile
Listed in the EU CosIng database as a safe skin-conditioning agent; widely tolerated in clinical settings up to 3% without adverse reactions.
Your Skin
Skin Compatibility
Our Assessment
Verdict
An exceptionally potent cell-signaling agent that delivers rapid results in elasticity and hydration when formulated at clinical concentrations.
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