Science
Mechanism of Action
This dual-action molecule functions by integrating a fragment of the SIRT1 longevity protein with a recombinant human-like growth factor (hGDNF). SIRT1 optimizes the cellular lifespan by facilitating DNA repair and bolstering antioxidant defenses, while the growth factor component signals fibroblasts to accelerate the synthesis of essential collagen and elastin fibers.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 In a 4-week clinical trial, 88% of users observed a measurable increase in skin resilience, while 84% noted a visible reduction in the depth of fine lines and wrinkles.
- 02 In-vitro analysis confirms the peptide supports NAD+ regeneration pathways, essential for maintaining skin density and a robust barrier function.
Transparency
Dusting Analysis
As a highly specialized, bioengineered fusion peptide, it is often included at minute 'label-claim' concentrations in mass-market products due to high raw material costs.
The Formula
Formulation
Stability
Highly sensitive to thermal degradation; must be processed below 40°C. Maintaining a stable pH between 5.5 and 7.5 is critical to prevent protein denaturing.
Synergies
- Hyaluronic Acid
- Niacinamide
- Non-proteolytic peptides
Conflicts
- L-Ascorbic Acid (due to low pH)
- Alpha Hydroxy Acids
- Proteolytic enzymes
- Strong oxidizing agents
Safety
Safety Profile
The barley-based production method eliminates the risk of animal-derived pathogens, making it a clean-biotech favorite. It is classified as safe for cosmetic use by the European Commission.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A cutting-edge, biotech-derived peptide that effectively bridges the gap between longevity science and visible skin rejuvenation.
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References
Sources