Science
Mechanism of Action
It operates through a sophisticated multi-pathway strategy: inhibiting pro-inflammatory enzymes like iNOS and COX-2 to calm reactive skin, neutralizing oxidative stress via free radical scavenging, and preserving the extracellular matrix by blocking the activity of collagenase and elastase. Additionally, it aids in complexion uniformity by interfering with tyrosinase, the enzyme responsible for melanin production.
Research
Clinical Evidence
High confidence0.1%
Key findings
- 01 Demonstrated up to 77.39% inhibition of collagenase and 59.26% inhibition of tyrosinase at 200 µg/mL.
- 02 In vitro results showed significant increases in mitochondrial activity and glutathione synthesis at concentrations as low as 0.01%.
- 03 Significant suppression of pro-inflammatory cytokines (TNF-α, IL-1β, and IL-6) and a 77.27% reduction in nitric oxide production at 50 µg/mL.
Transparency
Dusting Analysis
Because biological activity (mitochondrial stimulation) begins at a very low 0.01% threshold, many brands include it at 'label claim' levels below 0.01% where the anti-aging and anti-inflammatory benefits are negligible.
The Formula
Formulation
Stability
Displays robust stability across a wide pH spectrum. It is most frequently delivered in hydro-glycolic or hydro-ethanolic systems for optimal bioavailability.
Synergies
- Vitamin C
- Niacinamide
- Hyaluronic Acid
Safety
Safety Profile
Recognized as safe for cosmetic applications by the EU CosIng database; acute toxicity data (LD50 > 2000 mg/kg) suggests a high safety profile.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A high-performance botanical that bridges the gap between traditional soothing and modern precision anti-aging by protecting the dermal matrix and boosting cellular energy.
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