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BACILLUS/TETRAGONIA TETRAGONOIDES LEAF/STEM EXTRACT/VOLCANIC ASH FERMENT FILTRATE.

Valuable / SKIN CONDITIONING - MISCELLANEOUS

A high-performance bio-fermented complex that merges the botanical resilience of New Zealand Spinach with the mineral density of volcanic ash. This precision ingredient utilizes Bacillus subtilis to transform plant polysaccharides into highly bioavailable metabolites that significantly amplify antioxidant and anti-inflammatory activity.

Antioxidant Anti-inflammatory Skin Conditioning Sebum Regulation Barrier Recovery

Science

The fermentation process via Bacillus subtilis acts as a molecular catalyst, breaking down complex 6-methoxyflavonols and polysaccharides into smaller molecules for deeper epidermal penetration. This synergy inhibits the NF-κB and MAPK signaling pathways to arrest inflammatory cascades while the volcanic ash component introduces vital trace minerals like zinc and magnesium to regulate sebum and catalyze skin repair.


Research

High confidence
Effective range 0.1–5%
Optimal

1%

Key findings

  1. 01 Fermentation increases total polyphenol content by 1.3x and flavonoid concentration by 3.07x compared to non-fermented extracts.
  2. 02 Demonstrated significant inhibition of nitric oxide (NO) and proinflammatory cytokines at concentrations between 1.0% and 5.0%.
  3. 03 In vitro data confirms a marked reduction in skin irritation markers and accelerated barrier function recovery via MAPK pathway modulation.

Transparency

Not commonly dusted
Min. effective
0.1%
Red flag below
0.05%

With measurable in vitro efficacy starting as low as 0.1%, this ingredient is effective at modest concentrations; however, many formulations may use it below 0.1% simply for label claims, missing the 3.07x flavonoid boost found at higher therapeutic levels.


The Formula

Solubility
Water
Optimal pH 4.5 – 6.5
0 7 14

Stability

The filtrate is highly stable in aqueous systems but is thermolabile; it must be incorporated during the cooling phase (below 40°C) to prevent the degradation of bioactive fermentation metabolites.

Synergies

  • Niacinamide
  • Zinc PCA
  • Hyaluronic Acid
  • Probiotic Lysates

Conflicts

  • Strong oxidizing agents
  • Formulations with pH < 3.5 (potential mineral complex precipitation)

Safety

CIR Status
Not reviewed
Pregnancy
Safe
Sensitization risk Low

Listed in the EU COSMILE database. The biocompatibility of the fermentation process typically renders the extract non-sensitizing and suitable for reactive skin types.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A sophisticated biotechnological active that provides multi-pathway soothing and mineral enrichment, making it an excellent choice for modern, microbiome-conscious skincare.


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