Science
Mechanism of Action
This ingredient utilizes the enzymatic action of Bacillus subtilis to break down complex plant proteins into bioavailable peptides and amino acids. It generates natural lipopeptides like surfactin, which selectively inhibit pathogenic bacteria such as S. aureus while supporting beneficial microflora. Additionally, it leverages rosmarinic acid for antioxidant protection and soybean isoflavones to stimulate collagen synthesis and structural elasticity.
Research
Clinical Evidence
High confidence2%
Key findings
- 01 In vivo testing of a 2.0% concentration demonstrated a 15-20% improvement in skin barrier integrity and a significant reduction in Trans-Epidermal Water Loss (TEWL) over a 4-week period.
- 02 In vitro analysis at 1.0-3.0% showed a measurable reduction in inflammatory markers IL-1α and IL-6, alongside the inhibition of pathogenic bacterial growth.
Transparency
Dusting Analysis
To achieve the clinically validated 15-20% barrier improvement, a minimum concentration of 1.0-2.0% is required. Formulations using this extract at lower percentages (e.g., <0.5%) are likely utilizing it for marketing claims rather than functional microbiome or barrier repair benefits.
The Formula
Formulation
Stability
The extract is highly thermolabile; it must be incorporated during the cool-down phase of formulation at temperatures below 40°C to maintain the integrity of its bioactive peptides.
Synergies
- Ceramides
- Niacinamide
- Prebiotics
- Hyaluronic Acid
Conflicts
- Strong oxidizing agents
- Highly acidic environments (pH < 3.5)
- Highly alkaline environments (pH > 8.5)
Safety
Safety Profile
Composed of GRAS (Generally Recognized as Safe) components; no specific regulatory restrictions in the EU or US.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A scientifically robust fermented active that bridges the gap between microbiome health and physical barrier reinforcement at precise concentrations.
Related
Similar Ingredients
Finding similar ingredients…
References
Sources