Science
Mechanism of Action
This ingredient functions through a dual-action pathway: first, it synthesizes Gamma-Polyglutamic Acid (γ-PGA), which forms a breathable film to lock in moisture while inhibiting hyaluronidase to prevent the degradation of the skin’s natural hyaluronic acid. Second, the fermentation process breaks down soy isoflavones and rice polyphenols into smaller, high-bioavailability molecules that neutralize oxidative stress and modulate inflammatory markers.
Research
Clinical Evidence
High confidence3%
Key findings
- 01 Technical data indicates that at concentrations of 1-5%, the Bio-PGA produced by this complex provides moisture-retention levels that significantly outperform traditional hyaluronic acid.
- 02 In vitro testing showed 72.04% antioxidant activity at 100 μg/mL and significant antimicrobial effects against common skin pathogens at concentrations as low as 1.02 μg/mL.
- 03 Animal models studying Bacillus-fermented soybean extract demonstrated a marked reduction in atopic dermatitis-like lesions by suppressing IL-31 cytokine production and mast cell infiltration.
Transparency
Dusting Analysis
Because this is a complex fermented extract, many mass-market brands include it at 'label-claim' levels (below 1%) where its film-forming and hyaluronidase-inhibiting benefits are negligible.
The Formula
Formulation
Stability
The complex is highly stable in aqueous formulas but is heat-sensitive; it must be incorporated during the cooling phase (below 40°C) to maintain peptide integrity.
Synergies
- Hyaluronic Acid
- Glycerin
- Niacinamide
- Panthenol
Conflicts
- Cationic surfactants
- High electrolyte/salt concentrations
- Extreme pH environments below 4.0 or above 8.0
Safety
Safety Profile
All individual components (Rice Bran, Soybean, Sodium Glutamate, and Bacillus Ferment) are CIR-cleared and listed in the EU Cosing database as safe for cosmetic use.
Your Skin
Skin Compatibility
Our Assessment
Verdict
An elite multi-functional humectant that offers superior hydration longevity and enzymatic protection compared to standard hyaluronic acid.
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References
Sources