Science
Mechanism of Action
This ferment functions as a thermoregulatory agent to combat 'skin heat' while stimulating the synthesis of essential structural proteins like filaggrin, loricrin, and transglutaminase 1. By refining the Dermal-Epidermal Junction (DEJ) and inhibiting inflammatory cytokines such as TNF-α, it restores the lipid barrier and enhances deep-tissue elasticity.
Research
Clinical Evidence
High confidence35%
Key findings
- 01 Clinical evaluation of 30 Asian subjects demonstrated a 20% surge in hydration and a 13% reinforcement of the moisture barrier within 60 minutes of application.
- 02 A 4-week longitudinal study confirmed significant measurable improvements in skin density, wrinkle depth reduction, and overall tensile elasticity.
- 03 In vitro analysis at concentrations of 0.5-50 ppm showed marked upregulation of barrier-related proteins (FLG, LOR) and a stabilized DEJ index.
Transparency
Dusting Analysis
While biologically active at very low ppm levels for barrier protein signaling, the significant clinical benchmarks for wrinkle depth and density were achieved at a high 35% concentration. Products containing only trace amounts may offer antioxidant benefits but likely lack the intensive restorative power seen in clinical trials.
The Formula
Formulation
Stability
Produced via a patented 840-hour oil fermentation, this ingredient is highly stable in anhydrous and emollient systems. However, its bioactive glycopeptides are sensitive to thermal degradation.
Synergies
- Ceramides
- Squalane
- Peptides
Conflicts
- Strong oxidizing agents
- High-heat processing above 60°C
Safety
Safety Profile
The individual botanical components and Bacillus ferments are recognized as safe; dermatological screening confirms the complex is non-irritating even for reactive skin types.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A sophisticated, multi-targeted ferment that bridges traditional longevity medicine with modern biotechnology to significantly improve skin architecture and hydration.
Related
Similar Ingredients
Finding similar ingredients…
References
Sources