Science
Mechanism of Action
This filtrate functions as a multi-level skin modulator; it optimizes the skin microbiome, provides robust antioxidant defense, and uniquely regulates autonomic nerve activity in the dermal layers. By suppressing sympathetic nerve overactivity, it enhances microcirculation and vascular relaxation, effectively cooling inflammation and suppressing the itch response.
Research
Clinical Evidence
High confidence2%
Key findings
- 01 Demonstrated suppression of cutaneous itching and accelerated wound healing via neuro-regulation (Osaka University study).
- 02 Significant improvement in moisture retention (coercive humidity) and reduction in acne lesions at 1.0% concentration.
- 03 Enhanced barrier recovery and skin tone evening through high concentrations of natural ferulic acid and peptides.
Transparency
Dusting Analysis
While many brands list ferments for marketing appeal, clinical data confirms that efficacy for itch relief and barrier repair begins at 1.0%. Formulations containing less than this are likely 'dusting' the ingredient for the label claim without providing physiological benefits.
The Formula
Formulation
Stability
Heat-sensitive; must be incorporated during the cooling phase below 40°C to maintain the integrity of the bioactive peptides.
Synergies
- Niacinamide
- Hyaluronic Acid
- Ceramides
Conflicts
- Strong oxidizing agents
- Temperatures exceeding 50°C
- Extreme pH environments (<3.0 or >8.0)
Safety
Safety Profile
Recognized as safe by the CIR Expert Panel (2025). Its use in food-grade supplements further underscores its excellent biocompatibility and low toxicological profile.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A sophisticated precision ingredient that bridges the gap between microbiome health and neurological skin soothing.
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References
Sources