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Ingredient directory

Bacillus/lactobacillus/poncirus Trifoliata Fruit Extract Ferment Filtrate

A bio-fermented botanical active derived from the Hardy Orange fruit, specifically engineered to recalibrate the pore environment. Through precision fermentation with Bacillus and Lactobacillus, the extract's flavonoids are biotransformed to enhance bioavailability and therapeutic efficacy against pore-dwelling microbes.

Directory entry · Individual source review pending

This profile is awaiting an individual source review. Treat its ratings, dose estimates and compatibility labels as provisional; they are not medical advice or proof of a finished product’s effects.

pore tightening antimicrobial sebum regulation barrier recovery antioxidant

Science

Mechanism of Action

This ferment functions via a triple-action pathway: it effectively eliminates Demodex folliculorum mites to prevent pore distention, utilizes concentrated flavonoids like poncirin for immediate astringent tightening, and regulates sebum production by maintaining a healthy, acidic skin pH of approximately 4.5.

Research

Clinical Evidence

High confidence
Effective range 1–5%
Optimal

5%

Key findings

  1. 01 Clinical evaluation of the Anti Pore-Dex Complex demonstrated a 57.06% reduction in Demodex mite population after 4 weeks, increasing to a 69.25% reduction by week 8.
  2. 02 In vivo models indicate a significant suppression of inflammatory cytokines IL-6 and IL-8 alongside the upregulation of essential barrier proteins filaggrin and loricrin.

Transparency

Dusting Analysis

Commonly dusted
Min. effective
1%
Red flag below
0.5%

Because it is often part of a 'complex,' brands frequently include it at sub-clinical levels (<1%) for marketing claims. A concentration of at least 1-2% is required to achieve measurable antiparasitic and astringent benefits.

The Formula

Formulation

Solubility
Water
Optimal pH 4 – 6.5
0 7 14

Stability

Highly stable in water-based formulas; stability is maximized when formulated between pH 4.5 and 5.5 to mirror the skin's natural acid mantle.

Synergies

  • Niacinamide
  • Salicylic Acid
  • Hyaluronic Acid

Conflicts

  • Strong oxidizing agents
  • Alkaline environments (pH > 8.0) which degrade flavonoid integrity

Safety

Safety Profile

CIR Status
Safe as used
Max tested
5%
Pregnancy
Safe
Sensitization risk Low

Classified as a safe skin-conditioning agent under the 2024/2025 CIR review for Lactobacillus ferments.

Your Skin

Skin Compatibility

Yes Normal
No Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

A highly specialized, clinically-backed ferment that offers unique antiparasitic pore care and immediate textural refinement for oily and congested skin types.

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