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BABASSUAMIDOPROPALKONIUM CHLORIDE.

Valuable CAS 124046-05-5 / ANTISTATIC, HAIR CONDITIONING

A botanically-derived quaternary ammonium salt sourced from Babassu oil that serves as a multifunctional conditioning agent and delivery booster. It is prized in precision skincare for its ability to smooth the skin's micro-relief while simultaneously enhancing the transdermal flux of active bioactives.

antistatic conditioning agent penetration enhancer surfactant antimicrobial

Science

As a cationic (positively charged) molecule, it electrostatically adheres to the negatively charged keratinized surface of the skin, forming a microscopic antistatic and protective film. It acts as a penetration enhancer by temporarily reorganizing the lipid bilayer within the stratum corneum, and provides antimicrobial benefits by disrupting the cell membranes of opportunistic pathogens.


Research

High confidence
Effective range 0.1–0.5%
Optimal

0.4%

Key findings

  1. 01 Demonstrated a 4-log reduction in S. aureus populations when used in synergistic antimicrobial complexes.
  2. 02 Clinical wear studies of matrix patches confirmed a significant increase in active ingredient flux through the skin barrier at a 0.4% concentration.

Transparency

Not commonly dusted
Min. effective
0.1%
Red flag below
0.05%

In leave-on skincare, this ingredient is often capped at 0.1% for its preservative functions. However, to leverage its documented penetration-enhancing capabilities, concentrations closer to 0.4% are required; inclusion below 0.1% in a formula claiming 'enhanced delivery' may indicate label dusting.


The Formula

Solubility
Water
Optimal pH 3 – 7
0 7 14

Stability

Exhibits excellent thermal stability up to 70°C and remains stable in both aqueous and hydroalcoholic systems. Peak conditioning performance is achieved at a slightly acidic pH between 4.5 and 6.5.

Synergies

  • Quaternary ammonium compounds
  • Non-ionic surfactants
  • Hydroalcoholic delivery systems

Conflicts

  • Anionic surfactants (SLS, SLES)
  • Anionic thickeners (Carbomer)
  • Stearic acid soaps
  • High electrolyte concentrations

Safety

CIR Status
Safe as used
Max tested
0.1%
Pregnancy
Safe
Sensitization risk Low

Regarded as one of the gentlest quaternary salts due to its fatty acid profile from Babassu oil. While restricted to 0.1% as a preservative in leave-on products by the EU and FDA, it is safely used up to 5% in rinse-off applications.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An sophisticated, plant-derived multi-tasker that excels at improving product texture and maximizing the absorption of primary active ingredients.


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