Science
Mechanism of Action
This ingredient operates via a dual-action pathway: it creates a breathable, semi-occlusive surface shield for instant tightening and pollution defense, while simultaneously optimizing the intracellular NAD+/NADH ratio. By boosting NAD+ levels, it accelerates energy metabolism and promotes the synthesis of structural proteins like involucrin and filaggrin, leading to superior epidermal cohesion.
Research
Clinical Evidence
High confidence3%
Key findings
- 01 Demonstrated significant improvement in skin microrelief and radiance through enhanced epidermal differentiation (Guillon D, et al., 2025).
- 02 Observed induction of keratinocyte migration and fibroblast proliferation, supporting rapid recovery of cellular ATP levels (Kim JH, et al., 2019).
Transparency
Dusting Analysis
While often listed in 'ferment complexes' at trace amounts for marketing appeal, clinical benefits for barrier repair and metabolic signaling require a minimum concentration of 1%.
The Formula
Formulation
Stability
Highly robust in aqueous systems and thermostable up to 80°C. Maintains peak stability near the skin's natural pH of 5.5.
Synergies
- Niacinamide
- Hyaluronic Acid
- Peptides
Conflicts
- Amylase enzymes
- Strong oxidizing agents
- High-concentration electrolytes
Safety
Safety Profile
Classified as GRAS (Generally Recognized as Safe) and reviewed favorably under yeast-derived cosmetic ingredients.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A sophisticated fermented active that bridges the gap between instant surface smoothing and long-term cellular energy optimization.
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References
Sources