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AUREOBASIDIUM PULLULANS/DENDROPANAX MORBIFERUS (LEAF/STEM) EXTRACT FERMENT FILTRATE.

Valuable / SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

An advanced bio-fermented botanical complex that combines the resilience of the Korean 'Ginseng Tree' (Dendropanax morbiferus) with the restorative properties of the black yeast Aureobasidium pullulans. This high-performance filtrate delivers a multifaceted approach to skin health by optimizing cellular defense and enhancing structural integrity through natural polysaccharide synthesis.

Skin-Conditioning Brightening Anti-Aging Antioxidant Antimicrobial

Science

This ingredient operates through a four-tier pathway: first, it regulates melanogenesis by inhibiting tyrosinase enzymes to brighten skin tone; second, it utilizes pullulan polysaccharides to form an immediate physical tightening film; third, it suppresses MMP enzymes and pro-inflammatory signaling (JAK2/STAT) to protect the collagen matrix; and fourth, its rich phenolic profile neutralizes oxidative stress.


Research

High confidence
Effective range 1–20%
Optimal

5%

Key findings

  1. 01 Meta-analysis (2024) demonstrated significant reduction in hyperpigmentation with substantial tyrosinase and melanin inhibition (SMD 6.85 and 23.38 respectively).
  2. 02 In-vitro analysis (2025) confirmed the suppression of inflammatory markers iNOS and COX-2 along with the inhibition of collagen-degrading enzymes MMP-2 and MMP-8.
  3. 03 Microbiological screening (2024) validated potent antimicrobial properties against common skin pathogens S. aureus and S. epidermidis.

Transparency

Commonly dusted
Min. effective
1%
Red flag below
0.5%

To achieve measurable brightening and anti-inflammatory results, concentrations should ideally exceed 1.0%. Formulations including this ingredient near the end of the deck (below 0.5%) are likely utilizing it for marketing claims rather than physiological impact.


The Formula

Solubility
Water
Optimal pH 4 – 7
0 7 14

Stability

Highly stable in aqueous solutions; the inherent pullulan content improves formula texture and provides semi-occlusive barrier benefits.

Synergies

  • Niacinamide
  • L-Ascorbic Acid
  • Hyaluronic Acid
  • Peptides

Conflicts

  • High concentrations of ethanol
  • Strong cationic surfactants
  • Extreme pH environments (<3.0 or >8.0)

Safety

CIR Status
Safe as used
Max tested
90.7%
Pregnancy
Safe
Sensitization risk Low

Both the source botanical and the yeast ferment are considered safe for cosmetic application, with the primary byproduct (pullulan) holding FDA GRAS status.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A sophisticated, multifunctional fermented active that offers scientifically validated benefits for skin brightening, barrier support, and age-defense.


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