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ASTRAGALUS SINICUS EXTRACT.

Valuable CAS 223749-21-1 / SKIN CONDITIONING

A potent botanical bioactive derived from the Chinese milk vetch, specifically engineered to defend the skin's structural proteins from environmental and chronological degradation. It serves as a dual-action agent that simultaneously brightens hyperpigmentation and restores dermal elasticity by targeting the root causes of skin aging.

Antioxidant Anti-glycation Skin Brightening Dermal Matrix Protection Soothing

Science

This extract functions through a sophisticated multi-pathway approach: it neutralizes Reactive Oxygen Species (ROS) to prevent oxidative stress, inhibits the enzymatic breakdown of the skin matrix (collagenase and elastase), and suppresses tyrosinase activity to regulate melanin production. Additionally, it provides anti-glycation benefits by actively decomposing Advanced Glycation End-products (AGEs) that lead to skin rigidity.


Research

High confidence
Effective range 0.1–20%
Optimal

0.2%

Key findings

  1. 01 An 8-week clinical trial utilizing a 0.2% concentration demonstrated a 28.56 MI improvement in skin pigment and an 18.45 reduction in R-value coarseness.
  2. 02 In vitro analysis confirmed tyrosinase inhibition reaching up to 93.8% and a reduction in melanin concentration by 62.1%.
  3. 03 Dermal matrix protection was evidenced by 97.5% elastase inhibition and up to 99.0% collagenase inhibition at concentrations between 25-200 μg/mL.

Transparency

Commonly dusted
Min. effective
0.2%
Red flag below
0.05%

While many formulations include this extract at nominal levels for label claims, clinical data suggests a minimum threshold of 0.2% is required to achieve measurable improvements in skin texture and pigmentation.


The Formula

Solubility
Water
Optimal pH 4 – 7.5
0 7 14

Stability

Highly stable in both O/W and W/O emulsions; frequently delivered in a water-butylene glycol base to maximize cutaneous penetration.

Synergies

  • Antioxidants
  • Humectants
  • Peptides

Safety

CIR Status
Not reviewed
Max tested
20%
Pregnancy
Safe
Sensitization risk Low

Recognized as a safe skin conditioning agent by the EU CosIng database with an EWG Score of 1, indicating a very low hazard profile.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A high-performance botanical that bridges the gap between traditional herbalism and precision science, offering clinically backed anti-aging and pigment-correcting results.


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