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Moumoujus

ASTRAGALUS MEMBRANACEUS EXTRACT.

Valuable CAS 94166-93-5 / ANTIOXIDANT

A potent botanical adaptogen known as 'Huangqi,' this extract provides comprehensive cellular support to revitalize the skin's structural matrix. It is a high-performance multifunctional ingredient that bridges traditional herbalism with precision longevity science to address collagen loss and environmental stress.

Summary

Antioxidant Collagen Booster Soothing Agent Skin-Conditioning Anti-Senescence

Science

Mechanism of Action

This extract functions through a multi-pathway approach: it stimulates the synthesis of Type I and III collagen and promotes fibroblast proliferation while inhibiting Matrix Metalloproteinase-1 (MMP-1) to prevent protein degradation. At the cellular level, active components like Astragaloside IV and Cycloastragenol act as telomerase activators to combat senescence, while its anti-inflammatory properties suppress NF-κB pathways and reduce cytokine-induced irritation.

Research

Clinical Evidence

High confidence
Effective range 2–5%
Optimal

2.5%

Key findings

  1. 01 A 2% liposomal delivery concentration demonstrated a 20% increase in skin hydration and firmness within 14 days, with a 15% reduction in blemish-prone indicators after 42 days.
  2. 02 Human studies using a 5% concentration alongside Centella saponins showed an 8.7% increase in total collagen content and improved skin luminosity after 4 weeks.
  3. 03 In-vitro data at 0.1 mg/mL confirms significant downregulation of inflammatory markers including IL-6, IL-1β, and MMP-3.

Transparency

Dusting Analysis

Commonly dusted
Min. effective
1%
Red flag below
0.5%

While often included in trace amounts for 'label appeal' due to its botanical heritage, clinical improvements in skin density and structural firming typically require concentrations of 2% or higher. Formulations under 0.5% may offer antioxidant support but likely fail to deliver the reported structural rejuvenation benefits.

The Formula

Formulation

Solubility
Both
Optimal pH 4 – 8
0 7 14

Stability

The polysaccharides are thermally stable up to 60°C. However, key saponins like Astragaloside IV have poor water solubility and are most effective when delivered via liposomal systems or glycol-based phases to ensure deep skin penetration.

Synergies

  • Hyaluronic Acid
  • Peptides
  • Centella Asiatica Saponins
  • Glycerin

Conflicts

  • No specific chemical incompatibilities reported.

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
5%
Sensitization risk Low

Generally recognized as safe (GRAS) for oral consumption by the FDA and approved for cosmetic use in the EU. Data regarding use during pregnancy and lactation is currently insufficient.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

A highly effective regenerative botanical that offers measurable improvements in firmness and collagen density when formulated at active concentrations between 2% and 5%.

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