Science
Mechanism of Action
This extract functions as a multi-pathway antioxidant and anti-inflammatory agent. By utilizing a high concentration of chlorogenic and caffeic acids, it scavenges up to 97.1% of DPPH free radicals. It simultaneously inhibits the expression of pro-inflammatory mediators such as iNOS and COX-2, while suppressing cytokines like TNF-α and IL-6 to prevent lipid peroxidation and cellular stress.
Research
Clinical Evidence
Medium confidence0.1%
Key findings
- 01 Demonstrated 97.1% DPPH radical scavenging activity at a 0.1% concentration.
- 02 Inhibited Nitric Oxide and pro-inflammatory cytokines (IL-6, TNF-α) in dose-dependent ranges from 0.0005% to 0.004%.
- 03 Proven effective for topical skin conditioning and moisture retention between 0.1% and 1.5%.
Transparency
Dusting Analysis
Aster Scaber is effective at surprisingly low concentrations for anti-inflammatory benefits, but for meaningful antioxidant protection and conditioning, it should be formulated at or above 0.1%.
The Formula
Formulation
Stability
Highly sensitive to light and air; extract is prone to darkening over time. Use of chelating agents like Sodium Gluconate and opaque packaging is recommended.
Synergies
- Sodium Gluconate
- Tocopherol
- Caffeic Acid
Conflicts
- Strong oxidizing agents
- High pH environments (>7.0)
Safety
Safety Profile
Affirmed as GRAS (Generally Recognized as Safe) by the FDA. In vitro data shows no cytotoxicity at concentrations up to 0.05%.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A potent, multi-functional botanical that excels in soothing sensitive skin and providing significant oxidative protection.
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References
Sources