Science
Mechanism of Action
This multi-active filtrate functions by upregulating the expression of Filaggrin and Aquaporin-3 (AQP3) to fortify the skin barrier and optimize cellular hydration. Simultaneously, it stabilizes mRNA to stimulate Type I Collagen synthesis while suppressing inflammatory cytokines like IL-6 and IL-8.
Research
Clinical Evidence
High confidence1%
Key findings
- 01 In vivo testing at 1% concentration demonstrated measurable improvements in skin tone uniformity, gloss, and barrier integrity.
- 02 In vitro analysis showed that concentrations between 1.25% and 3% significantly increased protein levels responsible for moisture transport and structural support.
- 03 Low-dose concentrations (0.05% to 0.8%) were proven to enhance collagen gene transcription via the TGF-β/Smad pathway.
Transparency
Dusting Analysis
Because clinical anti-aging and anti-inflammatory benefits initiate at concentrations as low as 0.05%, this ingredient is rarely 'dusted,' though 1% is required for significant improvements in skin gloss and tone.
The Formula
Formulation
Stability
The filtrate is heat-stable up to 85°C and exhibits excellent stability in aqueous solutions over a 24-month shelf life. Store away from direct UV exposure.
Synergies
- Hyaluronic Acid
- Niacinamide
- Peptides
Conflicts
- Strong oxidizers
- Alkaline environments (pH > 8.0)
- High electrolyte concentrations (may cause turbidity)
Safety
Safety Profile
Classified as non-toxic and non-irritating; HRIPT testing at 10% concentration confirmed no potential for sensitization.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A high-performance bio-ferment that bridges traditional Japanese wisdom with modern molecular biology to deliver comprehensive hydration and anti-aging benefits.
Related
Similar Ingredients
Finding similar ingredients…
References
Sources