Science
Mechanism of Action
This filtrate operates through a multi-pathway approach to skin health. It upregulates Aquaporin-3 (AQP3) to facilitate water transport and stimulates Filaggrin (FLG) alongside tight junction proteins like CLDN1 and ZO-1 to reinforce the physical skin barrier. Additionally, it provides a rich profile of amino acids and ferulic acid to neutralize free radicals and promote collagen synthesis (COL1A1).
Research
Clinical Evidence
High confidence3%
Key findings
- 01 Enhanced AQP3 and Filaggrin protein levels by 71% and 51% respectively, significantly optimizing hydration and barrier repair.
- 02 Demonstrated significant increases in epidermal water content and a 28% upregulation of AQP3 expression.
- 03 When paired with Sialic Acid, collagen synthesis increased by 198% via TGF-β signaling pathways.
Transparency
Dusting Analysis
While many ferments are used at low levels for marketing, this specific dual-ferment shows measurable anti-aging benefits at concentrations as low as 0.25% when synergized, though 1.25%-3% is required for meaningful barrier support.
The Formula
Formulation
Stability
Exhibits excellent stability in aqueous environments with a typical 24-month shelf life. Formulations exceeding 5% may result in a tacky skin feel.
Synergies
- Sialic Acid
- Glycerin
- Hyaluronic Acid
- Niacinamide
Safety
Safety Profile
Classified as GRAS (Generally Recognized as Safe) and reviewed under the 2024 CIR yeast-derived ingredients category with no reported irritancy.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A highly biocompatible fermented active that excels at internal hydration and structural barrier support.
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References
Sources