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ASPERGILLUS/CAMELLIA JAPONICA SEED FERMENT EXTRACT FILTRATE.

Valuable / SKIN CONDITIONING

This bio-fermented active is a filtrate derived from Camellia japonica seeds, cultured with the Aspergillus fungus. This process enhances the bioavailability of key components like enzymes, amino acids, and antioxidants, delivering comprehensive benefits including improved hydration, radiance, and cellular resilience.

Antioxidant Humectant Skin conditioning Cellular regeneration support Immune system enhancement (skin) Collagen synthesis booster Elastin synthesis booster Barrier function strengthening Mitochondrial function improvement Senescent cell elimination

Science

This ferment filtrate uniquely targets skin health at a cellular level. It significantly promotes CXCL9 expression, facilitating the recruitment of CD4 CTL Memory T cells to precisely eliminate senescent fibroblasts, thereby enhancing the skin's intrinsic immune function. Furthermore, it activates the FUNDC1-mediated mitochondrial autophagy pathway, which is critical for optimizing mitochondrial function, mitigating reactive oxygen species accumulation, supporting Type III collagen and elastin synthesis, and strengthening the skin barrier through Claudin 1 repair.


Research

High confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Shiseido research indicates that fermented Camellia Seed Extract significantly upregulates CXCL9 expression, a crucial factor for recruiting CD4 CTL Memory T cells to specifically eliminate senescent fibroblasts, thereby enhancing skin immune function.
  2. 02 Research published in MDPI and PubMed Central demonstrates that Camellia japonica extract, particularly its active ingredient hyperoside, activates the FUNDC1-mediated mitochondrial autophagy pathway, leading to ameliorated mitochondrial dysfunction, reduced reactive oxygen species, alleviation of cellular S-phase blockade, reversal of senescence-associated β-galactosidase, promotion of Type III collagen and elastin synthesis, and repair of Claudin 1 related to skin barrier function.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 5 – 8
0 7 14

Stability

The ingredient is a clear, water-soluble liquid, with stability optimally maintained within a pH range of 5.0-8.0, as indicated by data for related Camellia japonica seed extracts.


Safety

CIR Status
Not reviewed
Sensitization risk Low

While a specific CIR report for ASPERGILLUS/CAMELLIA JAPONICA SEED FERMENT EXTRACT FILTRATE is unavailable, related ingredients like Camellia Japonica Seed Oil and Camellia japonica seed extract are recognized for their favorable safety profiles and low hazard ratings (e.g., EWG score of 1). This natural fermentation product is generally well-tolerated and considered safe for cosmetic applications, with biodegradable properties. A patch test is always advisable to confirm individual compatibility.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

This advanced fermented ingredient offers multi-faceted benefits, including immune system enhancement, senescent cell elimination, mitochondrial optimization, and robust support for collagen, elastin, and skin barrier integrity.


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