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Moumoujus

ASPERGILLUS/ANGELICA TENUISSIMA ROOT EXTRACT FERMENT EXTRACT.

Valuable / HUMECTANT, SKIN CONDITIONING, SKIN PROTECTING

This advanced fermented extract, derived from Angelica tenuissima root and Aspergillus oryzae, is a multi-active ingredient engineered to rejuvenate skin. It precisely targets key concerns such as photoaging, compromised skin barrier, dehydration, and uneven tone, promoting a visibly healthier and more resilient complexion.

Summary

Antioxidant Skin brightening Moisturizer/humectant Soothing Anti-aging Exfoliant Skin protecting Skin conditioning

Science

Mechanism of Action

This ingredient operates through several synergistic pathways to enhance skin vitality. It combats photoaging by enhancing extracellular matrix integrity, upregulating procollagen type-1 synthesis, and effectively suppressing matrix metalloproteinase-1 (MMP-1) and elastase expression. Its anti-inflammatory action involves attenuating inflammatory responses through increased photo-protective hemeoxygenase-1 and decreased pro-inflammatory COX-2 expression, alongside inhibiting inflammatory mediators like TARC, IL-6, TNF-α, and nitric oxide. Skin barrier function is fortified by boosting the expression of crucial components such as filaggrin, involucrin, loricurin, and SPTLC1. Hydration is significantly improved by increasing Aquaporin-3 (AQP3) expression, which facilitates epidermal water supply. Furthermore, it delivers skin lightening and anti-pigment effects by inhibiting melanin production, tyrosinase activity, and α-MSH induced melanogenesis, while also acting as a gentle exfoliant to encourage healthy cell turnover.

Research

Clinical Evidence

High confidence
Effective range 0.0125–0.1%
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Synergies

  • The fermentation process with Aspergillus oryzae has been shown to enhance the bioactivity and concentration of key active compounds like decursin and Z-ligustilide from Angelica tenuissima root.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Generally recognized as a safe cosmetic ingredient, approved for use by regulatory bodies such as the US FDA and the European Union Cosmetics Directive. Clinical studies demonstrated no significant cytotoxic or cell proliferative effects in human keratinocyte or fibroblast cells at concentrations up to 0.1% (1000 µg/mL). While considered low risk, individuals with heightened sensitivity may rarely experience mild skin irritation or redness.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

This multi-faceted fermented extract is a valuable addition to precision skincare, offering scientifically backed benefits for anti-photoaging, barrier enhancement, deep hydration, and even skin tone with a favorable safety profile.

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