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Moumoujus

ASPARAGUS OFFICINALIS STEM EXTRACT.

Valuable CAS 84649-90-1 / SKIN CONDITIONING

Asparagus Officinalis Stem Extract is a botanical active derived from the vibrant spears of asparagus, offering a multi-targeted approach to combating visible signs of skin aging. This precision ingredient is formulated to enhance skin elasticity, promote firmness, and support dermal thickness, revealing a revitalized and more youthful complexion.

Summary

Anti-aging Antioxidant Firming Elasticity-boosting Skin conditioning Anti-wrinkle Potential skin brightening Anti-inflammatory Photoaging protection

Science

Mechanism of Action

Asparagus Officinalis Stem Extract energizes and nourishes fibroblasts, crucial cells for skin health, thereby promoting rejuvenation, increasing elasticity, improving firmness, and enhancing dermal thickness. It actively targets signs of aging linked to cellular senescence and environmental pollution-induced stress by supporting collagen fibers and mitigating their degradation. The extract exhibits robust antioxidant properties and contains Vitamin C, contributing to a protective barrier against UV-induced damage. Furthermore, it demonstrates natural inhibition of tyrosinase activity, suggesting a potential role in skin brightening through reduced melanin synthesis. It powerfully inhibits key enzymes involved in skin degradation—matrix metalloproteinase-1 (MMP-1) by 83.4 ± 1.5%, elastase by 70.4 ± 4.1%, and hyaluronidase by 75.2 ± 1.0%. Additionally, it provides anti-photoaging benefits by suppressing pro-inflammatory pathways in skin fibroblasts exposed to hydrogen peroxide and UVB radiation, while also inducing Heat Shock Protein 70 (HSP70) expression and maintaining cellular redox balance.

Research

Clinical Evidence

Medium confidence
Effective range 2–5%
Optimal

2-5%

Key findings

  1. 01 At a recommended usage rate of 2-5% for a commercially available form (Regu-Scence), the extract helps restore younger-looking skin, delays signs of aging, gives energy and nutrients to fibroblasts, rejuvenating and increasing elasticity. It improves overall firmness and promotes thickness in dermal layers.
  2. 02 In vivo studies demonstrated a reduced appearance of two major signs of aging in the skin: collagen loss and dermis thinning.
  3. 03 In vitro studies showed significant inhibition rates of 83.4 ± 1.5% for matrix metalloproteinase-1 (MMP-1), 70.4 ± 4.1% for elastase, and 75.2 ± 1.0% for hyaluronidase, indicating potent anti-wrinkle activity.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 4.5 – 5.5
0 7 14

Stability

Store light-protected at a cool and dry place (59°-77°F).

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

The FDA does not regulate asparagus extract supplements as prescription drugs; however, long-term safety of topical application is not extensively studied. General safety assessments for products containing the extract indicate no GHS classification for hazards.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

With robust in vitro and some in vivo evidence supporting its anti-aging, firming, and protective actions, Asparagus Officinalis Stem Extract is a valuable addition to precision skincare formulations targeting visible signs of aging and environmental stress.

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