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ASCORBYL PHOSPHATE SUCCINOYL PENTAPEPTIDE-12.

Valuable CAS - / ANTIOXIDANT

ASCORBYL PHOSPHATE SUCCINOYL PENTAPEPTIDE-12 is an advanced ingredient that intelligently combines a stable vitamin C derivative with a powerful pentapeptide. This dual-action complex offers comprehensive benefits, including robust antioxidant protection, significant collagen stimulation, effective skin brightening, and enhanced cellular regeneration for improved skin health and youthful appearance.

Antioxidant Skin-conditioning Brightening Collagen synthesis booster Anti-aging Elasticity enhancer Wound healing support Hyperpigmentation reduction Keratinocyte proliferation promoter

Science

This innovative compound operates through a synergistic dual mechanism. The ascorbyl phosphate component acts as a potent antioxidant, effectively neutralizing free radicals and providing protection against environmental aggressors and UV-induced damage. It actively contributes to skin brightening by inhibiting melanin production and significantly stimulates collagen synthesis, which is crucial for maintaining skin firmness and elasticity. Concurrently, the succinoyl pentapeptide, which shares similarities with GHK (copper peptide), stimulates vital extracellular matrix components such as collagen, dermatan sulfate, chondroitin sulfate, and the small proteoglycan decorin. It revitalizes the replicative vitality of fibroblasts, attracts immune and endothelial cells to facilitate wound healing, and promotes keratinocyte proliferation, collectively improving skin elasticity, density, firmness, and reducing the appearance of fine lines, wrinkles, and hyperpigmentation. Furthermore, the peptide component possesses the ability to modulate human gene expression, contributing to overall skin vitality and resilience.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 6 – 8
0 7 14

Stability

As an ascorbyl phosphate derivative, this ingredient demonstrates improved stability compared to pure ascorbic acid, performing optimally within a neutral to slightly alkaline pH range of 6.0 to 8.0. It is sensitive to heat, moisture, oxygen, and light; therefore, it is recommended to incorporate the ingredient into formulations at temperatures below 40°C and to store finished products below 25°C. The presence of heavy metals can accelerate degradation, making the use of buffer systems and chelating agents advisable to maintain stability and prevent discoloration (e.g., turning beige to brown), which signifies deterioration.

Conflicts

  • low pH values
  • heat
  • moisture
  • heavy metals
  • oxygen
  • light

Safety

CIR Status
Not reviewed
Sensitization risk Low

While the Cosmetic Ingredient Review (CIR) Expert Panel has not conducted a specific review for ASCORBYL PHOSPHATE SUCCINOYL PENTAPEPTIDE-12, it has generally concluded other ascorbates and ascorbic acid derivatives to be safe for use in cosmetic products. EWG Skin Deep rates this specific ingredient with a 'LOW' concern level for potential issues such as cancer, allergies & immunotoxicity, developmental and reproductive toxicity, and usage restrictions, suggesting a favorable overall safety profile.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Valuable

ASCORBYL PHOSPHATE SUCCINOYL PENTAPEPTIDE-12 is a valuable ingredient, offering significant antioxidant, brightening, and anti-aging benefits through its combined vitamin C and peptide components, demonstrating broad skin compatibility and a favorable safety profile.


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