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ASCORBYL NICOTINATE.

Insufficient Data CAS 81489-64-7 / HUMECTANT, SKIN CONDITIONING

Ascorbyl Nicotinate is a novel ester combining Ascorbic Acid (Vitamin C) and Nicotinic Acid (Vitamin B3). This compound is theoretically designed to deliver the antioxidant and brightening benefits of Vitamin C alongside the microcirculation-enhancing and cellular vitality properties of Vitamin B3 derivatives.

Antioxidant Collagen Support Brightening Microcirculation Enhancement Skin Revitalization

Science

Functioning as a dual-action ingredient, Ascorbyl Nicotinate is anticipated to exert its effects through two primary pathways. Its Vitamin C moiety provides potent antioxidant protection against free radical damage, actively promotes collagen synthesis for improved skin structure, and aids in reducing hyperpigmentation by inhibiting melanin production. Concurrently, the Nicotinic Acid component is expected to induce vasodilation, thereby enhancing cutaneous blood flow. This increased microcirculation facilitates superior delivery of oxygen and vital nutrients to skin cells, supporting cellular repair, regeneration, and overall skin vitality.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

Specific data regarding typical usage concentrations or instances of 'dusting' (underdosing with ineffective amounts) for Ascorbyl Nicotinate are not available in the current research. Its efficacy concentrations are yet to be established through clinical studies.


The Formula

Solubility
Unknown
Optimal pH N/A
0 7 14

Stability

For optimal shelf-life, Ascorbyl Nicotinate should be stored dry, dark, and refrigerated (0-4°C for short term) or frozen (-20°C for long term). The precise optimal pH range for its stability within cosmetic formulations is not yet documented; however, analogous Vitamin C derivatives exhibit varied pH optima, with some stable in slightly acidic conditions (e.g., pH 5.5-6 for Ascorbyl Palmitate) and others across broader pH ranges (e.g., Ascorbyl Glucoside).


Safety

CIR Status
Not reviewed
Sensitization risk Unknown

Ascorbyl Nicotinate itself has not undergone specific safety assessments by regulatory bodies such as CIR, SCCS, or FDA. While general ascorbate compounds typically possess a favorable safety profile as reviewed by CIR, this does not directly extend to this specific ester, warranting further evaluation.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

Despite its compelling theoretical benefits derived from its parent compounds, Ascorbyl Nicotinate currently lacks specific clinical validation for efficacy and comprehensive safety assessments, rendering its precise role in precision skincare undefined.


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