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ASCORBYL ISOSTEARATE.

Valuable CAS - / SKIN CONDITIONING

Ascorbyl Isostearate is a highly stable, oil-soluble derivative of Vitamin C, designed for optimal skin penetration. It functions as a powerful antioxidant, protecting skin while actively promoting collagen synthesis and reducing hyperpigmentation for a visibly brighter and firmer complexion.

Antioxidant Skin Conditioning Skin brightening Anti-aging Collagen Boosting UV Protection (indirect) Barrier Support Anti-inflammatory

Science

This oil-soluble ester of Vitamin C efficiently penetrates the skin's lipid barrier, where it is enzymatically converted into active ascorbic acid. Its mechanism involves potent free radical scavenging, providing defense against both UV-A and UV-B induced cellular damage. It significantly accelerates collagen production, leading to anti-aging effects such as improved skin firmness and smoothness. Furthermore, by inhibiting tyrosinase activity, it effectively reduces melanin formation, resulting in skin lightening, diminished age spots, and a more even skin tone. It also supports the skin's natural barrier function and can help improve the appearance of impure or inflammatory skin conditions.


Research

High confidence
Effective range 0.01–10%
Optimal

N/A

Key findings

  1. 01 Demonstrates effectiveness as an antioxidant in cosmetic formulations, providing skin protection against UV-A and UV-B radiation, and preventing the oxidation of plant oils.
  2. 02 Commonly utilized at these levels for diverse applications including anti-aging treatments, moisturizers, skin brightening, dark spot correction, and general antioxidant support.

Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Ascorbyl Isostearate is a stable Vitamin C derivative, exhibiting good resistance to both acid and heat, alongside excellent color stability. Its oil solubility at room temperature (up to 10% in various organic solvents and oils like squalane, jojoba, and caprylic/capric triglycerides) allows for cold processing in most emollients. For long-term stability, it should be stored at 4°C in a dry, moisture-free, well-ventilated, and inert atmosphere.


Safety

CIR Status
Safe as used
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel, in their assessment of various ascorbic acid ethers and esters, concluded that Ascorbyl Isostearate is safe for use in current cosmetic practices and concentrations.


Your Skin

Yes Normal
No Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Valuable

Ascorbyl Isostearate is a valuable, stable, and well-tolerated oil-soluble Vitamin C derivative, offering multifaceted benefits for antioxidant defense, collagen synthesis, and skin brightening across a broad range of skin types.


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