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Moumoujus

ARUNCUS AETHUSIFOLIUS EXTRACT.

Insufficient Data CAS - / SKIN CONDITIONING

Aruncus aethusifolius extract, derived from a plant closely related to Aruncus dioicus, demonstrates promising in vitro activity. Research indicates its potential to address signs of aging by targeting critical enzymes and transcription factors, while also suggesting broader anti-inflammatory and antioxidant benefits observed in other Aruncus species.

Summary

Anti-aging Anti-inflammatory Antioxidant

Science

Mechanism of Action

Aruncus species, including Aruncus aethusifolius and its close relative Aruncus dioicus, exhibit a multi-faceted mechanism of action. They are understood to possess anti-inflammatory, anti-oxidant, and anti-aging properties. Specifically, Aruncus dioicus extract has shown to significantly reduce the expression of matrix metalloproteinases (MMP1, MMP2, and MMP3), enzymes responsible for collagen degradation. This anti-aging effect is further supported by its inhibition of phosphorylated-p38 (p-p38) and c-fos transcription factors, which are involved in cellular responses to stress and aging. Additionally, related species have been observed to modulate inflammatory pathways such as Akt/mTOR and JAK2/STAT3, contributing to their anti-inflammatory potential.

Research

Clinical Evidence

Medium confidence
Effective range 5–50%
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

No specific data regarding dusting potential for Aruncus aethusifolius extract in cosmetic formulations was identified.

The Formula

Formulation

Solubility
Unknown
Optimal pH N/A
0 7 14

Stability

Specific information regarding the optimal pH range for stability or general stability characteristics of Aruncus aethusifolius extract in cosmetic formulations is currently unavailable.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

Comprehensive safety assessments by regulatory bodies such as CIR or SCCS have not been identified for Aruncus aethusifolius extract. Furthermore, its status as a cosmetic ingredient or OTC active by the FDA is not available in current data.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

Aruncus aethusifolius extract shows promising in vitro anti-aging and anti-inflammatory potential based on studies of a closely related species, but direct clinical data and comprehensive safety information for this specific extract are currently insufficient to provide a definitive recommendation.

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