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ARTEMISIA PRINCEPS LEAF/EQUISETUM ARVENSE/HOUTTUYNIA CORDATA EXTRACT.

Valuable CAS - / SKIN CONDITIONING

A high-performance botanical complex combining Japanese Mugwort, Horsetail, and Heartleaf to address systemic skin reactivity and barrier depletion. This synergistic trio delivers a multi-pathway approach to calming inflammation while fortifying the skin's structural integrity through essential mineral and protein induction.

Skin conditioning Antioxidant Soothing Barrier Repair Anti-blemish

Science

This extract blend operates through three distinct biological pathways: it activates the AHR/OVOL1 signaling pathway to increase the production of essential barrier proteins filaggrin and loricrin; it utilizes the high silica content of Equisetum for cellular conditioning; and it employs flavonoids like quercitrin to mitigate the inflammatory response and provide targeted antibacterial support against C. acnes.


Research

High confidence
Effective range 1–3%
Optimal

1.5%

Key findings

  1. 01 In a 14-day human clinical trial, a 1% Artemisia-based formulation resulted in 77% of participants observing a visible reduction in redness and blemish-related swelling.
  2. 02 Technical data on the Comparex synergistic blend at 3% demonstrates significant acceleration in skin barrier recovery and broad-spectrum anti-inflammatory activity.
  3. 03 Pharmacological research indicates that the APE component specifically upregulates structural proteins to improve moisture retention in compromised, atopic skin conditions.

Transparency

Commonly dusted
Min. effective
1%
Red flag below
0.1%

Many formulations include this blend at negligible levels (below 0.1%) for 'label claims' due to its popular botanical associations. However, clinical data suggests that a minimum concentration of 1.0% is required to achieve meaningful anti-inflammatory and barrier-repair results.


The Formula

Solubility
Water
Optimal pH 5 – 7
0 7 14

Stability

Highly stable in water-based systems. To preserve the integrity of heat-sensitive polyphenols, it must be incorporated during the cooling phase at temperatures below 40°C.

Synergies

  • Ceramides
  • Niacinamide
  • Panthenol
  • Hyaluronic Acid

Conflicts

  • Strong oxidizing agents
  • Cationic surfactants

Safety

CIR Status
Safe as used
Max tested
0.4%
Pregnancy
Safe
Sensitization risk Low

While the individual components are traditionally safe, Equisetum Arvense is specifically CIR-reviewed for safety in leave-on products at concentrations up to 0.4%.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An expertly balanced botanical triad that provides robust clinical support for compromised barriers and reactive, acne-prone skin types.


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