Science
Mechanism of Action
The extract functions by inhibiting the release of key pro-inflammatory mediators, including Nitric Oxide (NO) and Prostaglandin E2 (PGE2), as well as cytokines like TNF-α and IL-6. Its rich profile of phenolic compounds and flavonoids, such as quercetin and kaempferol, neutralizes oxidative stress, while the volatile component capillene provides targeted antibacterial activity against pathogens like S. aureus.
Research
Clinical Evidence
Medium confidence1%
Key findings
- 01 A 2-week clinical study (Tao et al., 2021) demonstrated that a 1.0% concentration significantly reduced symptoms of acne and eczema through its combined antimicrobial and anti-inflammatory pathways.
- 02 Animal studies (Zarasvand et al., 2016) confirmed significant systemic antioxidant augmentation, specifically increasing SOD, CAT, and GSH enzyme levels.
Transparency
Dusting Analysis
In many commercial products, this extract is utilized at trace levels (<0.1%) primarily for fragrance or 'masking' purposes. To achieve the dermatological benefits observed in clinical data—specifically for acne and barrier repair—a concentration of at least 1.0% is recommended.
The Formula
Formulation
Stability
The extract is sensitive to thermal degradation and light exposure. For maximum potency, it should be formulated within an acidic pH range (4.0–5.5) and stored in opaque packaging.
Synergies
- Niacinamide
- Hyaluronic Acid
- Vitamin E
Safety
Safety Profile
Generally recognized as safe. Aqueous extraction methods further reduce the risk of potential irritants like estragole and methyleugenol, making it suitable for sensitive skin.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A high-performance botanical extract that excels at calming inflammation and balancing the skin microbiome when used at clinical concentrations.
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References
Sources