Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

ARTEMISIA ANNUA HERB OIL.

Valuable CAS 84775-74-6 / PERFUMING

A concentrated botanical oil derived from Sweet Wormwood, prized for its multi-dimensional approach to skin recovery. It combines potent antimicrobial properties with a profound ability to stabilize the skin barrier and reduce visible inflammatory markers.

Summary

Anti-inflammatory Antimicrobial Barrier Repair Antioxidant Soothing

Science

Mechanism of Action

This oil functions as a multi-pathway anti-inflammatory by suppressing pro-inflammatory mediators such as TNF-α, IL-6, and IL-8, while inhibiting the TSLP protein to alleviate itching. It provides broad-spectrum antimicrobial action against P. acnes and S. aureus by compromising microbial cell wall integrity and reinforces the skin barrier by upregulating filaggrin gene expression.

Research

Clinical Evidence

Medium confidence
Effective range 0.5–1%
Optimal

1%

Key findings

  1. 01 A 14-day clinical study utilizing a 1.0% concentration demonstrated significant reduction in acne blemish size and redness, with 77% of participants noting decreased swelling.
  2. 02 Human patch testing (30 subjects) confirmed that a 1.0% concentration is non-sensitizing and produces no irritation or erythema over 72 hours.
  3. 03 Application of related components showed a 63.90% increase in cuticle hydration and a 21.51% reduction in transepidermal water loss (TEWL) over 4 weeks.

Transparency

Dusting Analysis

Commonly dusted
Min. effective
0.5%
Red flag below
0.1%

Often utilized at trace amounts for its aromatic 'masking' properties or for marketing purposes. To achieve the clinically validated benefits for acne reduction and barrier repair, a concentration near 1.0% is required.

The Formula

Formulation

Solubility
Oil
Optimal pH 5 – 6.5
0 7 14

Stability

Highly volatile and sensitive to thermal degradation; must be processed cold or added during the cooling phase (<60°C). Prone to oxidation if exposed to light or air; optimal stability is achieved in emulsions between pH 5.5 and 6.3.

Synergies

  • Barrier-repairing lipids
  • Soothing antioxidants
  • Chitosan (for stabilized emulsion complexes)

Conflicts

  • High manufacturing temperatures (>60°C)
  • Strong oxidizing agents
  • Highly alkaline environments (pH > 8.0)

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
1%
Sensitization risk Low

While generally well-tolerated at 1.0%, high-camphor chemotypes can pose health concerns if used in excessive doses. Listed by the FDA as a flavoring agent.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

An exceptional bioactive for reactive and blemish-prone skin that bridges the gap between traditional herbalism and modern dermatological precision.

Related

Similar Ingredients

Finding similar ingredients…