Science
Mechanism of Action
This extract facilitates skin repair through a dual-action pathway: it inhibits inflammatory mediators like NF-kB and COX-1/2 while simultaneously activating fibroblasts to synthesize collagen. It further protects the skin matrix by balancing Matrix Metalloproteinases (MMPs), specifically boosting MMP-2 and reducing MMP-9 to ensure structural integrity during the healing process.
Research
Clinical Evidence
High confidence2.5%
Key findings
- 01 Clinical evaluation of a 2.5% standardized gel confirmed significant tissue repair and anti-inflammatory safety in human subjects (Jorge et al., 2020).
- 02 In vivo studies at 1.0% concentration demonstrated accelerated wound contraction and increased fibroblast proliferation (Siraichi et al., 2013).
Transparency
Dusting Analysis
Because it is an exotic botanical, it is frequently used at 'label-claim' levels (below 0.1%). However, clinical data suggests a minimum threshold of 1.0% is required to trigger meaningful fibroblast proliferation and collagen modulation.
The Formula
Formulation
Stability
While biologically active up to pH 7.4, its anthocyanin pigments are most stable and maintain color integrity in acidic environments (pH 2.0-3.5). Stability in complex formulas is best maintained through liposomal encapsulation.
Synergies
- Ascorbic Acid
- Hyaluronic Acid
- Peptides
Conflicts
- High pH environments
- Strong oxidizing agents
Safety
Safety Profile
Independent toxicology profiles indicate the extract is non-genotoxic and non-irritating, supporting its use in sensitive skin applications.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A highly effective botanical for inflammation control and dermal remodeling, provided it is formulated at clinically relevant percentages.
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