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ARCTIUM LAPPA SEED EXTRACT.

Valuable CAS 84012-13-5 / HAIR CONDITIONING, SKIN CONDITIONING

Arctium Lappa Seed Extract, derived from burdock seeds, is a multifaceted botanical ingredient recognized for its soothing, brightening, and protective properties. Rich in compounds like arctiin and arctigenin, it effectively addresses concerns from inflammation and oxidative stress to uneven skin tone.

Summary

Skin conditioning Antioxidant Anti-inflammatory Skin brightening Astringent Soothing Hydrating Barrier support Antimicrobial Antifungal

Science

Mechanism of Action

This extract, particularly through active compounds like arctiin and arctigenin, delivers significant anti-inflammatory and antioxidant benefits. It actively suppresses neutrophil migration during inflammation, reducing key inflammatory markers such as IL-6, TNF-α, and IL-1β, alongside mitigating edema and nitric oxide production. As a potent antioxidant, it neutralizes free radicals, thereby protecting against premature aging. Arctigenin specifically inhibits melanin production by repressing tyrosinase expression, leading to a brighter complexion. The extract also possesses astringent qualities beneficial for balancing oil, soothes irritated skin, reduces redness, strengthens the skin barrier, provides deep hydration, and exhibits potential antimicrobial and anti-fungal effects.

Research

Clinical Evidence

Medium confidence
Effective range 1–5%
Optimal

N/A

Key findings

  1. 01 A clinical study utilizing a 1% Arctigenin-Enriched Burdock Seed Oil (ABSO) lotion demonstrated improved skin brightness and tone evenness in human subjects, with excellent tolerability.
  2. 02 In vitro studies with 2-5% ABSO confirmed non-toxicity and a significant increase in cell viability within an EpiDerm™ tissue model. Furthermore, a reduction in melanin content was observed in an in vitro MelanoDerm™ tissue model.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

No specific optimal pH range for the stability of ARCTIUM LAPPA SEED EXTRACT in cosmetic formulations has been identified. However, Arctigenin-enriched burdock seed oil (ABSO) maintains its activity, suggesting good stability, particularly in oil-based formulations. Lignans like arctiin and arctigenin are the principal active compounds, and ethanolic extracts are also employed.

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
5%
Sensitization risk Moderate

Generally considered safe for cosmetic use, with a recommended maximum concentration of 5%. While a 1% Arctigenin-Enriched Burdock Seed Oil (ABSO) lotion was well-tolerated in human skin, and 2-5% ABSO was non-toxic in in vitro tests, some individuals may experience minor allergic reactions such as skin irritation or itching, warranting a patch test. The European Cosmetics Regulation acknowledges its safety for use within specified dosages.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Arctium Lappa Seed Extract is a valuable botanical offering comprehensive benefits for skin health, including brightening, soothing inflammation, and antioxidant protection, making it suitable for a wide range of skin types.

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