Science
Mechanism of Action
This extract operates through a dual-pathway approach: it neutralizes reactive oxygen species (ROS) to prevent cellular oxidation while inhibiting pro-inflammatory mediators such as TNF-α and IL-6. Furthermore, it protects dermal integrity by reducing DNA damage from UVB exposure and decreasing the formation of cyclobutane pyrimidine dimers (CPD).
Research
Clinical Evidence
Medium confidence0.01%
Key findings
- 01 Stimulated antioxidant gene expression and successfully mitigated oxidative stress in human keratinocytes.
- 02 Demonstrated potent anti-inflammatory action by suppressing nitric oxide levels in cellular models.
Transparency
Dusting Analysis
Because biological activity is recorded at very low concentrations (as low as 0.005%), many brands include it at 'trace' levels for marketing claims. For precision results, it should be formulated at 0.008% or higher to ensure anti-inflammatory benefits.
The Formula
Formulation
Stability
Highly stable in hydro-ethanolic solutions; requires opaque, UV-protective packaging to prevent the degradation of bioactive phenolic compounds.
Synergies
- Vitamin C
- Centella Asiatica
- Broad-spectrum UV filters
Conflicts
- Strong oxidizing agents
Safety
Safety Profile
Recognized as safe for topical application and classified as a flavoring substance by the FDA; listed as a safe antioxidant in the EU COSMILE database.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A high-performance botanical for reducing inflammatory markers and cellular DNA damage, particularly effective in sensitive and reactive skin protocols.
Related
Similar Ingredients
Finding similar ingredients…