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AQUILARIA AGALLOCHA WOOD EXTRACT.

Valuable / HAIR CONDITIONING, SKIN CONDITIONING

Derived from the rare agarwood tree, this botanical powerhouse provides a sophisticated approach to environmental defense and cellular repair. It bridges the gap between traditional apothecary wisdom and modern molecular biology, offering significant anti-inflammatory and restorative benefits.

Skin Conditioning Antioxidant Anti-inflammatory Antimicrobial

Science

This extract operates through a multi-pathway approach: it downregulates pro-inflammatory mediators such as COX-2 and various interleukins (IL-6, IL-8) while inhibiting the NF-κB signaling pathway. Additionally, it provides robust antioxidant protection by neutralizing reactive oxygen species (ROS) and physically compromises the cell walls of harmful bacteria to maintain a healthy skin microbiome.


Research

Medium confidence
Effective range 0.005–0.125%
Optimal

0.01%

Key findings

  1. 01 Demonstrated suppression of oxidative stress in H2O2-induced keratinocytes at concentrations as low as 50 μg/mL (MDPI, 2023).
  2. 02 Identified as an effective regenerative agent for anti-aging and skin repair within the 50-100 μg/mL range.
  3. 03 Established antibacterial efficacy against S. epidermidis with a Minimum Inhibitory Concentration (MIC) of 1.25 mg/mL.

Transparency

Commonly dusted
Min. effective
0.005%
Red flag below
0.001%

Due to its high cost and aromatic profile, it is frequently included at 'label claim' levels. However, clinical data suggests it is biologically active at very low thresholds (starting at 0.005%), making it difficult to distinguish between functional use and marketing 'dusting' without precise transparency.


The Formula

Solubility
Both
Optimal pH 4.5 – 7
0 7 14

Stability

The extract contains volatile sesquiterpenes and polyphenols that are prone to oxidation; it requires airless packaging or stabilization with antioxidants.

Synergies

  • Antioxidants
  • Soothing agents

Conflicts

  • Strong oxidizing agents

Safety

CIR Status
Not reviewed
Max tested
1%
Pregnancy
Safe
Sensitization risk Moderate

Contains natural fragrant compounds like limonene and linalool, which may trigger sensitivities in individuals reactive to essential oil components.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A high-performance botanical that provides meaningful antioxidant and anti-inflammatory activity even at micro-concentrations.


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References