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APIUM GRAVEOLENS CALLUS EXTRACT.

Valuable / ANTIOXIDANT, SKIN PROTECTING

A high-performance plant stem cell extract derived from celery that targets the structural integrity of the dermal matrix. It is specifically engineered to revitalize 'passive' skin tissues, making it a premier choice for remodeling scars and improving deep-set textural irregularities.

Dermal Remodeling Collagen Stimulant Skin Protectant Antioxidant

Science

This extract functions by stimulating the synthesis of essential Extracellular Matrix (ECM) proteins, notably Collagen I, III, and IV. Its primary point of differentiation is its ability to induce SPARC (Secreted Protein Acidic and Rich in Cysteine) expression, a critical protein that ensures collagen fibers are correctly assembled and organized for improved skin density and tissue repair.


Research

High confidence
Effective range 0.1–2%
Optimal

2%

Key findings

  1. 01 In vitro testing confirmed a 34% increase in Collagen I production and significant stimulation of SPARC protein at a 1.0% concentration.
  2. 02 In vivo clinical trials using 2.0% concentration demonstrated a visible reduction in the appearance of mature 'white' stretch marks and a measurable improvement in skin elasticity through tissue remodeling.

Transparency

Commonly dusted
Min. effective
1%
Red flag below
0.5%

Because plant stem cell extracts carry high marketing appeal, they are frequently used at 'claim' levels (below 0.1%). To achieve the structural remodeling and collagen-boosting benefits seen in clinical data, a concentration of 1.0% to 2.0% is required.


The Formula

Solubility
Water
Optimal pH 4 – 7.5
0 7 14

Stability

Heat-sensitive; must be incorporated during the cool-down phase below 40°C to preserve the integrity of the secondary metabolites and bioactivity.

Synergies

  • Peptides
  • Retinoids
  • Vitamin C

Safety

CIR Status
Not reviewed
Max tested
2%
Pregnancy
Safe
Sensitization risk Low

While not yet formally reviewed by the CIR, it holds an FDA UNII and has a documented safety profile for topical use within the recommended 2.0% limit.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A highly precise bio-active for structural skin repair and collagen organization, particularly effective for addressing scars and loss of density.


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