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APHANIZOMENON FLOS-AQUAE EXTRACT.

Valuable / HUMECTANT, SKIN CONDITIONING

A nutrient-dense blue-green algae extract sourced from Klamath Lake, functioning as a sophisticated botanical alternative to traditional retinoids. It provides intensive skin-resurfacing benefits and cellular protection without the inflammatory side effects typically associated with Vitamin A derivatives.

Retinoid-like resurfacing Biological antioxidant Epidermal regenerator Humectant Anti-inflammatory

Science

This extract operates by modulating gene expression involved in epidermal differentiation, specifically targeting proteins such as filaggrin and loricrin to refine skin texture. It contains high concentrations of C-Phycocyanin and mycosporine-like amino acids (MAAs) which neutralize reactive oxygen species (ROS) and inhibit NF-κB nuclear translocation, effectively suppressing the release of pro-inflammatory cytokines like IL-1β.


Research

High confidence
Effective range 2–5%
Optimal

3%

Key findings

  1. 01 A 21-day clinical trial involving 40 female participants utilizing a 3% concentration showed a significant decrease in wrinkle depth and complexity, alongside a marked smoothing of skin microrelief.
  2. 02 In vitro testing at 2% concentration confirmed the modulation of dermal matrix proteins, including vimentin and MMPs, mimicking the structural regenerative mechanism of retinol.
  3. 03 Human keratinocyte studies demonstrated a 10% reduction in ROS formation when pre-treated with the extract and exposed to blue light and oxidative pollutants.

Transparency

Commonly dusted
Min. effective
2%
Red flag below
0.5%

Due to its high cost and 'superfood' marketing appeal, this ingredient is frequently included at sub-clinical levels (below 1%) purely for label claims. Efficacy for wrinkle reduction and retinoid-like gene expression requires at least 2-3%.


The Formula

Solubility
Water
Optimal pH 4.5 – 8.5
0 7 14

Stability

The extract is thermolabile; it must be incorporated during the cooling phase of production (below 35°C) to prevent the degradation of bioactive pigments and proteins. Store finished products in opaque packaging away from direct light.

Synergies

  • Niacinamide
  • Hyaluronic Acid
  • Peptides
  • Non-acidic antioxidants

Conflicts

  • Strong oxidizing agents
  • Formulations with pH below 4.0
  • High heat processing (>40°C)

Safety

CIR Status
Safe as used
Max tested
5%
Pregnancy
Safe
Sensitization risk Low

Recognized as safe for both topical and dietary use (GRAS). Clinical patch tests at 3% confirm no significant irritancy or sensitization potential.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An exceptional multi-functional extract for those seeking the smoothing benefits of retinol without the irritation, provided it is formulated at a 3% threshold and protected from heat.


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