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AORTA EXTRACT.

Valuable CAS 225234-42-4 / SKIN CONDITIONING

A biologically active extract derived from vascular tissue, specifically chosen for its high concentration of structural proteins like soluble elastin and collagen. This ingredient acts as a sophisticated humectant that creates a protective, moisture-binding film to reinforce the skin's extracellular matrix.

Skin conditioning Humectant Film-former Matrix support

Science

Aorta Extract functions as a high-affinity skin conditioner and water-binding agent. By delivering a precise complex of glycosaminoglycans (GAGs) and amino acids, it supports the skin’s natural elastic fibers while inhibitory biomolecules (ranging from 27 to 66 kDa) help prevent the premature enzymatic degradation of native elastin.


Research

Medium confidence
Effective range 0.1–2%
Optimal

1%

Key findings

  1. 01 In-vitro analysis confirms the presence of soluble elastin and GAGs that actively support the extracellular matrix structure.
  2. 02 Biochemical research identifies specific inhibitory molecules within the extract that regulate biomineralization and protect structural proteins from environmental breakdown.

Transparency

Commonly dusted
Min. effective
0.1%
Red flag below
0.05%

Due to its animal-derived nature and complexity, it is often included at negligible levels for label claims; efficacy requires at least 0.1% to provide meaningful skin-conditioning benefits.


The Formula

Solubility
Water
Optimal pH 5 – 7.5
0 7 14

Stability

Highly sensitive to thermal denaturation; must be added during the cool-down phase of formulation. Protein precipitation occurs in highly acidic or alkaline environments.

Synergies

  • Hyaluronic Acid
  • Soluble Collagen
  • Niacinamide

Conflicts

  • Ethanol (>15%)
  • Proteolytic enzymes
  • Strong acids (pH < 4.0)
  • Strong bases

Safety

CIR Status
Not reviewed
Pregnancy
Safe
Sensitization risk Low

Must be sourced from certified BSE-free (Bovine Spongiform Encephalopathy) materials to meet rigorous EU and FDA safety standards for animal-derived biologicals.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A potent biological source of elastin-support molecules that excels in moisture retention and structural preservation when formulated within a stable pH range.


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