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Moumoujus

ANTRODIA CINNAMOMEA FRUITING BODY EXTRACT.

Valuable / ANTIOXIDANT

A rare medicinal mushroom extract native to Taiwan, prized for its exceptionally high concentration of triterpenoids and polysaccharides. It functions as a potent multi-corrective agent that accelerates epidermal recovery while providing significant anti-inflammatory and age-defying benefits.

Summary

Antioxidant Soothing agent Skin-conditioning Barrier repair Anti-inflammatory

Science

Mechanism of Action

This extract operates through a multi-pathway approach: it activates PPARδ to stimulate cellular regeneration and wound repair, while simultaneously inhibiting MAPK and NF-κB pathways to suppress pro-inflammatory cytokines like IL-6 and TNF-α. Furthermore, its rich antcin content provides robust antioxidant protection and inhibits tyrosinase activity to manage hyperpigmentation.

Research

Clinical Evidence

High confidence
Effective range 0.1–1%
Optimal

1%

Key findings

  1. 01 Topical application (0.1%–1.0%) demonstrated enhanced wound healing via PPARδ activation and inflammatory regulation.
  2. 02 In vitro data confirms significant reduction in nitric oxide and pro-inflammatory markers at concentrations as low as 1-10 μg/mL.
  3. 03 A 2024 clinical study of a nano-emulsion delivery system showed an 18.6% reduction in wrinkle depth and a 25.1% improvement in barrier function within 14 days.

Transparency

Dusting Analysis

Commonly dusted
Min. effective
0.1%
Red flag below
0.05%

Due to its high cost and potency, brands often include this ingredient at trace levels ('dusting') below 0.1% for marketing claims. Clinical data suggests a minimum of 0.1% is required for tangible physiological benefits in tissue repair.

The Formula

Formulation

Solubility
Both
Optimal pH 5 – 6.5
0 7 14

Stability

Thermally sensitive; bioactive polysaccharides and triterpenes may degrade if exposed to temperatures exceeding 50°C. Formulations should be stored in opaque packaging to prevent phenolic oxidation.

Synergies

  • Panthenol
  • Ceramides
  • Niacinamide
  • Hyaluronic Acid

Conflicts

  • Strong oxidizing agents
  • High heat processing
  • Highly alkaline environments (pH > 8.0)

Safety

Safety Profile

CIR Status
Not reviewed
Pregnancy
Safe
Sensitization risk Low

Extensive oral safety data (NOAEL of 3,000 mg/kg/day) and a long history in traditional topical use suggest a high safety profile. It is clinically validated as non-irritating and hypoallergenic.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

A high-performance botanical extract that bridges the gap between traditional medicine and precision dermatology, particularly effective for barrier repair and inflammation-driven aging.

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