Science
Mechanism of Action
This extract stimulates the synthesis of Tenascin-X, a crucial glycoprotein that regulates the spacing and organization of collagen fibers within the extracellular matrix. By enhancing the production of Type I Collagen and Elastin while increasing the contractile force of dermal fibroblasts, it restores the skin's internal tension and architectural integrity.
Research
Clinical Evidence
High confidence2%
Key findings
- 01 Clinical trials using 2% SKINectura™ recorded a 65% reduction in neck wrinkle area and a 61% reduction in depth over 28 days.
- 02 In vivo testing demonstrated a 36% improvement in eye-area wrinkle appearance within 28 days.
- 03 Measurable lifting and smoothing effects on the neck and jawline were observed as quickly as 1 hour after application.
Transparency
Dusting Analysis
While this ingredient is highly effective at 2%, its premium cost often leads brands to include it at 'label claim' concentrations (under 0.5%). At these levels, the structural lifting and Tenascin-X stimulation benefits are significantly compromised.
The Formula
Formulation
Stability
The extract is exceptionally robust, remaining stable in heat up to 85°C. However, for maximum biological activity, it is ideally incorporated during the cool-down phase below 40°C.
Synergies
- Peptides
- Vitamin C
- Retinoids
Safety
Safety Profile
Manufacturer safety data, including HET-CAM and patch testing, confirms the extract is non-irritating and non-sensitizing even at concentrations up to 10% (diluted).
Your Skin
Skin Compatibility
Our Assessment
Verdict
A high-precision botanical essential for targeting the 'Y-zone' (neck and jawline) through the innovative pathway of Tenascin-X stimulation.
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