Science
Mechanism of Action
It reduces inflammation by inhibiting pro-inflammatory pathways and suppressing cytokines, while also combating oxidative stress through ROS scavenging. The extract may also protect collagen by inhibiting MMP-1 activity.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 Fitoterapia 2014, 98: 174-178
- 02 ACS Food Science & Technology 2023
Transparency
Dusting Analysis
No data indicates common dusting practices or concerns for this ingredient.
The Formula
Formulation
Stability
Active triterpenoids are organic-soluble, while other beneficial compounds are water-soluble, allowing for broad formulation. It demonstrates optimal stability in slightly acidic to neutral pH environments (pH 4.5-6.5), supporting skin barrier health.
Conflicts
- Strong oxidizing agents
- Highly alkaline conditions (pH ```json { "name": "ANGELONIA ANGUSTIFOLIA FLOWER/LEAF/STEM EXTRACT", "slug": "angelonia-angustifolia-flower-leaf-stem-extract", "description": "This botanical extract is rich in potent anti-inflammatory triterpenoids like Lupeol. It offers significant skin-healing benefits and helps calm irritation.", "mechanism": "It reduces inflammation by inhibiting pro-inflammatory pathways and suppressing cytokines, while also combating oxidative stress through ROS scavenging. The extract may also protect collagen by inhibiting MMP-1 activity.", "clinical_efficacy": { "confidence": "high", "key_studies": [ "Fitoterapia 2014, 98: 174-178", "ACS Food Science & Technology 2023" ], "dose_range_max": 1, "dose_range_min": 0.01, "optimal_percentage": null }, "dusting_analysis": { "commonly_dusted": false, "explanation": "No data indicates common dusting practices or concerns for this ingredient.", "dusting_threshold": null, "red_flag_percentage": null }, "formulation": { "solubility": "both", "stability_notes": "Active triterpenoids are organic-soluble, while other beneficial compounds are water-soluble, allowing for broad formulation. It demonstrates optimal stability in slightly acidic to neutral pH environments (pH 4.5-6.5), supporting skin barrier health.", "synergies": [], "conflicts": [ "Strong oxidizing agents", "Highly alkaline conditions (pH > 8.0)" ], "optimal_ph_max": 6.5, "optimal_ph_min": 4.5 }, "safety": { "cir_status": "not reviewed", "sensitization_risk": "low", "notes": "This extract is traditionally recognized as safe for topical use. No specific safety restrictions or maximum concentrations have been established by regulatory bodies like CIR or SCCS.", "max_concentration": null, "pregnancy_safe": null }, "skin_compatibility": { "irritancy": "low", "comedogenicity": "low", "dry": true, "normal": true, "oily": true, "sensitive": true }, "functions": [ "Antioxidant", "Soothing", "Anti-inflammatory" ], "synonyms": [], "common_uses": [ "Soothing creams and lotions", "Anti-aging serums", "Acne treatments (due to anti-inflammatory properties)", "Post-sun care products" ], "verdict": { "rating": "valuable", "summary": "A highly valuable botanical extract with strong anti-inflammatory and antioxidant properties, making it excellent for soothing, healing, and protecting all skin types." } } ```
Safety
Safety Profile
This extract is traditionally recognized as safe for topical use. No specific safety restrictions or maximum concentrations have been established by regulatory bodies like CIR or SCCS.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A highly valuable botanical extract with strong anti-inflammatory and antioxidant properties, making it excellent for soothing, healing, and protecting all skin types.
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