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ANGELICA KEISKEI ROOT EXTRACT.

Valuable CAS - / SKIN CONDITIONING

Angelica Keiskei Root Extract, also known as Ashitaba, is a multi-functional botanical ingredient. It offers significant antioxidant, brightening, and anti-inflammatory benefits for skin health.

Antioxidant Skin conditioning Soothing Anti-inflammatory

Science

This extract contains prenylated chalcones and flavonoids, acting as a potent antioxidant by neutralizing ROS and inducing autophagy. It inhibits tyrosinase for melanin reduction and provides anti-inflammatory effects by regulating redox signaling.


Research

Medium confidence
Effective range 8–10%
Optimal

N/A

Key findings

  1. 01 An 8% cream effectively inhibited melanin increase in UVB-exposed skin, comparable to 4% hydroquinone.
  2. 02 A 10% methanol extract showed moderate antibacterial activity against acne-causing bacteria like S. epidermidis and S. aureus.

Transparency

Not commonly dusted

There is no available data suggesting that Angelica Keiskei Root Extract is commonly dusted in formulations.


The Formula

Solubility
Both
Optimal pH 4.5 – 6.5
0 7 14

Stability

Extracts are often obtained using water or ethanol-water, maintaining physical stability in serum gels for at least 28 days within a skin-neutral pH. Chalcones may be sensitive to extreme pH and light.

Conflicts

  • Strong oxidizing agents

Safety

CIR Status
Not reviewed
Sensitization risk Low

While not formally reviewed by CIR for cosmetic use, FDA categorized Ashitaba sap as GRAS at up to 0.834% for food. The EU also authorized stem juice as a novel food in 2024.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Angelica Keiskei Root Extract is a valuable ingredient, demonstrating potent antioxidant, brightening, and anti-inflammatory properties with good skin compatibility.


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References